UNEXPECTED CORONARY THROMBOSIS INDUCED BY ANTIPHOSPHOLIPID SYNDROME (HUGHES SYNDROME) CASE REPORT (Abstract): Antiphospholipid syndrome (APS), one of the most common states of acquired hypercoagulability, is diagnosed by the persistent presence of antiphospholipid antibodies and recurrent episodes of vascular thrombosis. We present the case of a 39-year-old man late-presenting for cardiac rehab...

normal 0 false false false en-us x-none ar-sa background: contrast induced kidney injury is an acute renal dysfunction that is secondary to the administration of radio contrast media. the purpose of this study was to evaluate the levels of urotensin-ii (ut-ii) and endothelin-i (et-i) after contrast media administration in patients undergoing percutaneous coronary interventions. materials and me...

background: atherosclerosis is a multifactorial disorder with chronic inflammatory conditions in which immune cells play a significant role in its pathogenic process. regulatory t cells (treg), as a part of immune system, are involved in controlling autoimmune and inflammatory diseases. quantitative and/or functional alteration of tregs has been shown to play an atheroprotective role and may al...

Acute disseminated encephalomyelitis (ADEM) is a monophasic clinical syndrome, characterized by immune-mediated demyelination of central nervous system neurons, which yield extensive damage in the brain and spinal cord.It usually affects children and young adults following infections or immunization. Here we describe a 9- year-old Fars female presented with acute onset of psychotic disorder, o...

Coronary artery fistulas (CAFs) are rare defects in the coronary circulation system that usually diagnosed incidentally with cardiac imaging. Although prognosis of is highly variable, complications to which they predispose patients ultimately determining factor. The authors describe a case 56-year-old male, smoker, hospitalised for worsening dyspnoea on progressively smaller efforts, context ac...

I have read with great interest the article entitled “Major Depression and Acute Coronary Syndrome-Related Factors” by Figueiredo et al.,1 recently published in journal. The investigators found a 23% prevalence of patients with acute coronary syndrome (ACS) meeting the diagnostic criteria for major depressive disorder (MDD). Women were more susceptible to develop MDD in the sample group of ACS ...

The traditional view of atherosclerosis has recently been expanded from a predominantly lipid retentive disease to a coupling of inflammatory mechanisms and dyslipidemia. Studies have suggested a novel role for polymorphonuclear neutrophil (PMN)-dominant inflammation in the development of atherosclerosis. Human neutrophil peptides (HNPs), also known as alpha-defensins, are secreted and released...

Dear editor Regarding the duration of supplement therapy in our study which has been published in the Avicenna J Phytomed, 2019; 9(1): 1-9, “The effects of curcumin on the prevention of atrial and ventricular arrhythmias and heart failure in patients with unstable angina” (Dastani et al., 2019),  some critical flaws has been mentioned. Primarily, we are grateful for the consi...

Cardiovascular diseases represent the leading cause of mortality in pregnancy. They are classified as direct (acute onset disease) or indirect (worsening of pre-existing cardiac disease). This overview is focused on acute coronary syndrome (ACS) in pregnancy and the post-partum period. ACS in this setting is a rare condition, but in the last two decades its incidence has grown. This phenomenon ...