Cutaneous leishmaniasis is endemic in the tropics and neotropics. It is often referred to as a group of diseases because of the varied spectrum of clinical manifestations, which range from small cutaneous nodules to gross mucosal tissue destruction. Cutaneous leishmaniasis can be caused by several Leishmania spp and is transmitted to human beings and animals by sandflies. Despite its increasing...

cutaneous leishmaniasis is a common tropical dermatose with diverse clinical presentations. at times, it may appear in unusual shape or unusual site that causes diagnostic challenge. we reported a case of unusual presentation of cutaneous leishmaniasis which appeared as an ulcer on the lower lip of a ten-year-old boy. the diagnosis was confirmed by identifying leishmania parasites at ulcer smea...

BACKGROUND Leishmaniasis is an endemic disease in Iran. Although many treatments have been suggested for this disease, there hasn't been an effective and safe treatment yet. Regarding the healing effect of honey in the chronic ulcers and its reported therapeutic effect in cutaneous leishmaniasis, we performed a study to better evaluate the efficacy of honey in cutaneous leishmaniasis and its fi...

Human leishmaniasis is a spectral disease that includes asymptomatic self-resolving infection, localized skin lesions, and progressive visceral leishmaniasis. With some overlap, visceral and cutaneous leishmaniasis are usually caused by different species of Leishmania. This review focuses on host responses to infection with the species that cause visceral leishmaniasis, as they contrast with sp...

7. Aoun K, Bouratbine A. Cutaneous leishmaniasis in North Africa: a review. Parasite. 2014;21:14. http://dx.doi.org/10.1051/parasite/ 2014014 8. Douba M, Mowakeh A, Wali A. Current status of cutaneous leishmaniasis in Aleppo, Syrian Arab Republic. Bull World Health Organ. 1997;75:253–9. 9. Yehia L, Adib-Houreih M, Raslan WF, Kibbi AG, Loya A, Firooz A, et al. Molecular diagnosis of cutaneous le...

The effects in vivo of the bisphosphonate drug pamidronate, used in bone resorption therapy, were investigated in an experimental model of cutaneous leishmaniasis. Pamidronate at an intraperitoneal dose of 10 mg/kg/day for 5 days effects a radical cure of cutaneous leishmaniasis in Balb/c mice, as evidenced by long-term disappearance of lesions; disappearance of amastigotes in lesion sites, as ...

American cutaneous leishmaniasis is in full geographic expansion in Brazil and it is considered among the infectious and parasitic diseases of utmost importance worldwide, not only by its frequency, but mainly by therapeutic difficulties, deformities and sequelae that may result. In the state of Rio de Janeiro, the first autochthonous case of American cutaneous leishmaniasis was registered by R...

We report an imported case of cutaneous leishmaniasis in a 37-year-old man from Saudi Arabia caused by Leishmania major. He presented with non-healing nodulo-ulcerative lesions with a "volcanic crater" on the lower limbs. It was clearly cutaneous leishmaniasis - a rare disease in China - as reflected by the patient's clinical history, the lesions' morphology, histopathological examination, cult...

conclusions l. major is the main species responsible for cutaneous leishmsniasis in four geographical regions of khuzestan province southwestern of iran and nested pcr can be used for diagnosis and leishmania species identification. results 138 (94.5%) out of 146 cases of four regions were l. major and 8(5.5%) were l. tropica. 57.97% of l. major cases were male and 42.03% were female. 87.5% of ...

background : cutaneous leishmaniasis is one of the prevalent health problems in tropical and subtropical areas including iran. therefore, it is essential to identify the prevalence and new foci of this disease in different regions of iran. this study aimed to determine the epidemiology of cutaneous leishmaniasis by active surveillance in elementary schools in pakdasht city, southeast of tehran,...