Severe respiratory failure (including acute lung injury and acute respiratory distress syndrome) caused by 2009 H1N1 influenza infection has been reported worldwide. Refractory hypoxemia is a common finding in these patients and can be challenging to manage. This review focuses on nonventilatory strategies in the advanced treatment of severe respiratory failure and refractory hypoxemia such as ...

COPD is characterized by a progressive decline in lung function and mental and physical comorbidities. It is a significant burden worldwide due to its growing prevalence, comorbidities, and mortality. Complication by bronchial-pulmonary infection causes 50%-90% of acute exacerbations of COPD (AECOPD), which may lead to the aggregation of COPD symptoms and the development of acute respiratory fa...

Rhinoviruses are the major cause of the common cold and a trigger of acute asthma exacerbations. Whether these exacerbations result from direct infection of the lower airway or from indirect mechanisms consequent on infection of the upper airway alone is currently unknown. Lower respiratory infection was investigated in vitro by exposing primary human bronchial epithelial cells to rhinoviruses ...

The pathogen of the new 2019 coronavirus disease (COVID-19), sever acute respiratory syndrome 2 (SARS-Cov-2), presented a significant risk to health care. WHO has described SARS-CoV-2 infection outbreak as an international public emergency. main damage caused by with was known be lung infections. Previous research revealed that liver is prevalent in patients infected additional widely zoonotic ...

BACKGROUND An association between infections and vascular events has been observed, but the specific effect of influenza and influenza-like illnesses on triggering acute myocardial infarction (AMI) is unclear. METHODS Episodes of first AMI from 1 January 2003 through 31 July 2009 were identified using linked anonymized electronic medical records from the Myocardial Ischaemia National Audit Pr...

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection continues to prevail as the deadliest epidemic of 21st century and an unprecedented global crisis. Global statistics July 2021 revealed that, more than 196 million people worldwide have been infected 4.19 succumbed SARS-CoV-2.

Respiratory syncytial virus is the major cause of lower respiratory tract infection in children. Adults who are immunocompromised, aged, institutionalized, and/or have underlying medical diseases may be at risk for severe RSV infection. Intubated adults in an MICU were evaluated for evidence of RSV infection. Respiratory secretions were analyzed by cell culture and RSV EIA. Serologic testing wa...

Swine flue is a highly contagious acute respiratory disease caused by a subtype of influenza A virus. Herein we present three patients with H1N1 infection complicated with pulmonary thromboembolism. The patients had chest pain and unexplained dyspnea. Imaging studies showed bilateral hilar predominance. Computed tomographic angiography confirmed bilateral thromboembolism (an unusual presentatio...

The Coronavirus disease 19 (COVID-19) pandemic has resulted in considerable mortality and morbidity worldwide since identified Wuhan late 2019. It was named severe acute respiratory syndrome coronavirus 2 (SARS-CoV2), which is a causative agent of human tract infection. detailed mechanism host immune response pathogenesis to this virus not fully elucidated. In review, we recapitulate the charac...

Chronic respiratory infections are a major cause of morbidity and mortality, most particularly in Cystic Fibrosis (CF) patients. The recent finding that gastro-esophageal reflux (GER) frequently occurs in CF patients led us to investigate the impact of bile on the behaviour of Pseudomonas aeruginosa and other CF-associated respiratory pathogens. Bile increased biofilm formation, Type Six Secret...