نتایج جستجو برای: acute thrombocytopenia

تعداد نتایج: 516851  

Journal: :Critical care medicine 2009
Andreas Link Matthias Girndt Simina Selejan Alexander Mathes Michael Böhm Hauke Rensing

OBJECTIVE Argatroban, a direct thrombin inhibitor, was evaluated for anticoagulation in continuous renal replacement therapy (CRRT) in critically ill patients with heparin-induced thrombocytopenia type II and acute renal failure. The investigation focused on predictors for the maintenance doses of argatroban with efficacy and safety of argatroban being secondary outcomes. DESIGN Prospective, ...

2017
Chia-Ter Chao Hung-Bin Tsai Chih-Kang Chiang Jenq-Wen Huang

BACKGROUND Few studies have addressed risk factors for acute kidney injury (AKI) in geriatric patients. We investigated whether thrombocytopenia was a risk factor for AKI in geriatric patients with medical illnesses. METHODS A prospective cohort study was conducted, by recruiting elderly (≥65 years) patients who visited the emergency department (ED) for medical illnesses during 2014. They all...

2015
Sabine Topka Joseph Vijai Michael F. Walsh Lauren Jacobs Ann Maria Danylo Villano Pragna Gaddam Gang Wu Rose B. McGee Emily Quinn Hiroto Inaba Christine Hartford Ching-hon Pui Alberto Pappo Michael Edmonson Michael Y. Zhang Polina Stepensky Peter Steinherz Kasmintan Schrader Anne Lincoln James Bussel Steve M. Lipkin Yehuda Goldgur Mira Harit Zsofia K. Stadler Charles Mullighan Michael Weintraub Akiko Shimamura Jinghui Zhang James R. Downing Kim E. Nichols Kenneth Offit

Somatic mutations affecting ETV6 often occur in acute lymphoblastic leukemia (ALL), the most common childhood malignancy. The genetic factors that predispose to ALL remain poorly understood. Here we identify a novel germline ETV6 p. L349P mutation in a kindred affected by thrombocytopenia and ALL. A second ETV6 p. N385fs mutation was identified in an unrelated kindred characterized by thrombocy...

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