Chikungunya most often is a self-limiting febrile illness with polyarthritis and the virus is not known to be neurotropic. We are reporting a case of chikugunya fever presenting as acute demyelinating encephalomyelitis(ADEM) which is very rare.

Abstract Background Postvaccination acute disseminated encephalomyelitis (ADEM) may develop 2–30 days after vaccination. However, ADEM following pneumococcal vaccination has never been reported. Case presentation We report a 73‐year‐old woman with She developed fever and consciousness disturbance 17 the second administration of 23‐valent polysaccharide vaccine (PPSV23). Head magnetic resonance ...

INTRODUCTION Unvaccinated patients with history of splenectomy are prone to fulminant courses of Streptococcus pneumoniae-associated bacterial meningitis. Besides direct brain damage those patients may additionally suffer from parainfectious syndromes, notably vasculitis and acute disseminated encephalomyelitis (ADEM). Differentiation and treatment of these immunological reactions is challengin...

BACKGROUND The CNS inflammatory demyelinating disorders of childhood include both self-limited and lifelong conditions, which can be indistinguishable at the time of initial presentation. Clinical, biologic, and radiographic delineation of the various monophasic and chronic childhood demyelinating disorders requires an operational classification system to facilitate prospective research studies...

Dear Editor, Acute disseminated encephalomyelitis (ADEM) is a monophasic acute nonvasculitic inflammatory demyelinating disorder of the central nervous system that is characterized by diffuse neurologic signs and symptoms coupled with evidence of multifocal demyelination lesions on neuroimaging.1 The onset of ADEM usually follows a viral infection or immunization after a mean period of 7–14 day...

Acute disseminating encephalomyelitis (ADEM) is a treatable inflammatory, demyelinating disorder of the central nervous system. Early application of steroids has been shown to reduce morbidity, therefore, early diagnosis is highly desirable. Magnetic resonance imaging (MRI) is the imaging modality of choice for establishing the diagnosis along with the clinical presentation. The aim of this rep...

Multiple sclerosis (MS) and acute disseminated encephalomyelitis (ADEM) are demyelinating inflammatory diseases, considered to have a striking pathophysiological resemblance. However, due to the differences in both clinical course and clinical approaches, it is important to differentiate between the two conditions, to plan further investigations and therapy protocols. These diseases have simila...