BACKGROUND
Adenovirus vectors have lately been highlighted in gene therapies. We investigated the oncolytic effects of a chimeric adenovirus type 5 (Ad5) with replacement of Ad5 fiber knob with adenovirus type 35 (Ad35) fiber knob (Ad5F35) on human renal cell carcinoma (RCC).
MATERIALS AND METHODS
The conditionally replicating Ad5F35 vector was constructed and infected into RCC cell lines 786...
