Inside Cover: Marrying acyclic diene metathesis polymerization and BiTEMPS chemistry offers a simple method to prepare tailor-made polymer with precise control over the primary structure. Pivotally, macromolecule, decorated sulfur-nitrogen bonds in each repeating unit, exhibits light-responsive reversible homolytic dissociation of disulfide linkage, where specific treatment (e.g., anaerobic con...

Prostate cancer is the most common type of diagnosed in men worldwide and second leading cause death after lung cancer. Testosterone dihydrotestosterone (DHT) have been known to play an essential role prostate Androgen receptor (AR) binding ligand allows homodimerization translocation nucleus, which acts as a transcription factor for androgen-responsive genes such PSA (Prostate-specific antigen...

The study aims to identify the most responsible compound for antiinflammation activity from Mitragyna speciosa leaves. Seventeen compounds previously reported have been isolated leave were virtually screened against human 5-lipoxygenase protein and analyzed according their binding energies. native ligand used was arachidonic acid, mitragynine found be strongest (Pubchem ID: 3034396). In additio...