Background: Clinicians are commonly tasked to evaluate adnexal masses. Both radiography and serum markers are useful in the counseling of patients regarding management options. Inhibin is one of several tumor markers used in the evaluation of adnexal masses given its known association with sex cord stromal tumors, specifically granulosa cell tumors. Case 1: 68 year old G6P6 Caucasian female who...

Background: Adnexal torsion results in ischemia of structures distal to twisted pedicle and acute onset of pain is responsible for about 3% of all gynecologic emergencies. Ovarian torsion classically occurs in a pathological enlarged ovary, as with cancer, but diagnosis remains a challenge. Objective: Our purpose was to evaluate clinical risk factors predictive of torsion with gangrenous adnexa...

OBJECTIVE To compare the feasibility and safety of the laparoscopic management of adnexal masses appearing preoperatively benign with those suspicious for malignancy. METHODS Retrospective study of 694 women that underwent laparoscopic management of an adnexal mass. RESULTS Laparoscopic management of an adnexal mass was completed in 678 patients. Six hundred and thirty five patients had ben...

OBJECTIVE We sought to determine the validity of cancer antigen 125 (CA-125) and the risk of malignancy index (RMI) in the diagnosis of ovarian cancer in women presenting with adnexal lesions of various histopathology types. METHODS This retrospective cross- sectional study included all women with adnexal lesions who were evaluated at the Royal Hospital, Oman, between January 2012 and Decembe...

Cervical carcinoma infrequently involves the uterine corpus or adnexa. Metastatic adenocarcinoma (AC) to the ovaries can be difficult to distinguish from primary ovarian tumors, and metastatic squamous cell carcinoma (SCC) to these sites has not been well described. Our aim was to provide a detailed description of the morphologic patterns of adnexal and corpus involvement by cervical carcinoma....

OBJECTIVE The aim of this study was to evaluate the use of a Risk of Malignancy Index (RMI) in primary evaluation of patients with adnexal masses. METHODS The RMI is based on menopausal status, ultrasonographic findings, and serum CA 125 level. A cutoff level of 200 was chosen as the threshold for referral for centralized primary surgery. This setup was evaluated by sensitivity, specificity, ...

Primary malignant schwannoma of the small and large intestine is an extremely rare disease. Therefore, we are going to report an aggressive multifocal malignant intestinal schwannoma in a 66-year old female patient, that was primarily diagnosed as the gynecological tumor that, even after the surgical treatment, had a very quickly recurrence. Small intestine tumors may show images similar to an ...

Objective: To prospectively assess the diagnostic performance of Doppler ultrasound and grayscale imaging for the discrimination of benign and malignant adnexal masses. Study design: Observational study. Duration: January 2002 to December 2003. Setting: Mother and Child Health (MCH) Center, Unit II, Pakistan Institute of Medical Sciences, Islamabad, Pakistan. Subjects: Patients with an adnexal ...

Extranodal marginal zone lymphomas (EMZL) are the most common lymphomas in the ocular adnexa. The etiology and potential role for antigenic stimulation in these lymphomas are still controversial. We have examined IGHV gene usage and mutations in 67 Chlamydophila psittaci-negative ocular adnexal EMZL. Clonal IGHV gene sequences were identified in 43 tumors originating from the orbit (19), conjun...

PURPOSE To estimate interobserver agreement with regard to describing adnexal masses using the International Ovarian Tumor Analysis (IOTA) terminology and the risk of malignancy calculated using IOTA logistic regression models LR1 and LR2, and to elucidate what explained the largest interobserver differences in calculated risk of malignancy. EXPERIMENTAL DESIGN One hundred and seventeen women...