Gastric cancer is a heterogeneous disease with diverse histological and genomic subtypes, making it difficult to demonstrate treatment efficacy in clinical trials. However, recent efforts have been made identify molecular biomarkers prognostic predictive implications better understand the broad heterogeneity of gastric develop effective targeted therapies for it. HER2 overexpression, HER2/neu a...

OBJECTIVE Recent advances in surgical treatment of oesophageal cancer have improved the prognosis of early, locally advanced oesophageal cancer. Primary cancer from oesophageal graft is rare, but has been detected in long-term survivor. We analyzed data from patients who developed primary gastric cancer in an oesophageal graft to evaluate strategies of treatment and their outcomes. METHODS We...

background: gastric cancer is the fifth most common cancer in the world and the third leading cause of death from cancer worldwide. this study aims to assess the epidemiology of gastric cancer in ardabil province, iran. methods: this was a descriptive cross-sectional study performed on 1056 patients with gastric cancer registered in the ardabil cancer registry. data were collected by a checklis...

Gastric cancer is often discovered incidentally with late complication (1). The prognosis for gastric cancer is poor and, in most industrialised countries, the survival is only 10% after 5 years from diagnosis (2). The most recent estimates of global cancer incidence indicate that in 1990 stomach cancer was the second most frequent cancer in the world after lung cancer with about 800,000 new ca...

PURPOSE Borrmann type IV gastric cancer is still detected at an advanced stage and survival rates for these patients remain poor. The purpose of this study was to provide valuable prognostic and surgical information on patients with Borrmann type IV gastric cancer. METHODS We compared the clinicopathological features of Borrmann type IV gastric cancer with those of other types of gastric canc...

Gastric cancer is the one of most prevalent common malignant tumors and the common cause of cancer related death in East Asia. Gastric cancer is associated with a short time to recurrence and a short survival period after recurrence. In China, age-standardized 5-year relative survival for gastric cancer was only 27.4 % (Zeng et al., 2014). Although advances in diagnostic and treatment technolog...

From 1966 to 1985, 2130 patients with gastric cancer were admitted to our surgical department. Among these cancers, gastric cancer following partial gastrectomy for benign gastroduodenal lesion were present in 22 (1%) patients. The original pathology was gastric ulcers in 64% (14 patients), duodenal ulcers in 23% (5 patients), combined gastric and duodenal ulcers in 9% (2 patients), and leiomyo...

BACKGROUND This study aimed at examining the association of gene silencing and promoter methylation of glutathione peroxidase 1 (GPX1) and glutathione peroxidase 3 (GPX3) in gastric cancer cells and determined the clinical significance of GPX1 and GPX3 expression loss in gastric cancer tissue. MATERIALS AND METHODS Analysis of mRNA expression was carried out by reverse transcription-polymeras...

We report a case of primary fibroepithelial polyps (FEPs) in the middle of both ureters in a patient with advanced gastric cancer and acute renal failure. Ureteral FEPs are rare benign lesions, and multiple, bilateral lesions are extremely rare. To our knowledge, this report is the seventh case of bilateral FEPs in the literature. Our case has clinical implications because FEPs should be consid...

INTRODUCTION Gastric cancer is one of the most common cancer-related causes of death. This is mainly due to the lack of good noninvasive method/biomarkers suitable for early-tumour diagnosis and planning of further therapy modalities. Chemokines play an important role in cancer progression and metastasis formation. In gastric cancer patients, clinical relevance of CXCL12 and CCL5 level has been...