OBJECTIVE Antibiotics are the most common drugs causing adverse events and they lead to problems to patients and additional costs of the health system. The aim of the study was to evaluate the occurrence of adverse events to antibiotics in inpatients of a hospital. METHODS An extensive drug monitoring was conducted in adult inpatients taking antibiotics in the city of Maringá, Southern Brazil...

BACKGROUND Medication errors cause a large number of adverse drug events with negative patient health outcomes and are a major public-health burden contributing to 18.7-56 % of all adverse drug events among hospitalized patients. The aim of this study was to assess the incidence and determinants of medication errors and adverse drug events among hospitalized children. METHODS A prospective ob...

INTRODUCTION Patients initiated on highly active antiretroviral therapy (HAART) generally remain on medication indefinitely. A modification in the HAART regimen may become necessary because of possible acute or chronic toxicities, concomitant clinical conditions, development of virological failure or the advent of adverse drug events. The study documents adverse drug events of HIV-positive Ghan...

Tolerability of a drug should be regarded as important as its efficacy. In all four phases of drug development evaluation of adverse events is important. Recommendations for assessment of adverse events in acute and prophylactic clinical drug trials in migraine are given. Tolerability may be indirectly assessed using measures of general well-being and eight such tools are presented. Finally, re...

UNLABELLED Older hospitalized patients are at risk of experiencing adverse events including, but not limited to, hospital-acquired pressure ulcers, fall-related injuries, and adverse drug events. A significant challenge in monitoring and managing adverse events is lack of readily accessible information on their occurrence. PURPOSE The objective of this retrospective cross-sectional study was ...

Incorrect use of drugs may cause adverse events with serious consequences for patients. Adverse event (Adverse events) refers to an event related to the care process and which involves an injury to the patient, unintended and undesirable. Errors in drug therapy (also called error of therapy) are predictable events that may cause or lead to the inappropriate use of the drug or a threat to hospit...