BACKGROUND Androgenetic alopecia (AGA) is one of the most common chronic problems seen by dermatologists worldwide. It is characterized by progressive hair loss, especially of scalp hair, and has distinctive patterns of loss in women versus men, but in both genders the central scalp is most severely affected. It often begins around puberty and is known to effect self-esteem and the individual's...

The American Gastroenterological Association (AGA) Institute Medical Position Panel consisted of the authors of the technical review, a community-based gastroenterologist (Stephen W. Hiltz, MD, MBA, AGAF), an insurance provider representative (Edgar Black, MD, Medical Director, Policy Resources Technology Evaluation Center, BlueCross BlueShield Association), a general surgeon (Irvin M. Modlin, ...

Acinetobacter glutaminase-asparaginase (AGA) and Escherichia coli asparaginase were compared for their effects on plasma and tissue levels of amino acids, ammonia, and glutamyl transferase activity in the mouse. Free asparagine was depleted similarly in plasma and tissues by both enzymes. AGA treatment produced partial depletion of glutamine concentrations in muscle, spleen, small intestine, an...

The AGA Institute Medical Position Panel consisted of the authors of the technical review (Stuart J. Spechler, MD, AGAF, Prateek Sharma, MD, Rhonda F. Souza, MD, AGAF, John M. Inadomi, MD, AGAF, Nicholas J. Shaheen, MD, MPH, AGAF), the chair of the Medical Position Panel (John I. Allen, MD, MBA, AGAF), the chair of the AGA Institute Practice Management and Economics Committee and the AGA Instit...

BACKGROUND The aim of this study was to assess the possible associations between female androgenetic alopecia (AGA), insulin resistance and health-related quality of life (HRQOL)-linked factors in women. We hypothesized that not only the mental aspects but also certain physical aspect of women's health, such as insulin resistance, have an important role in the determination of HRQOL among women...

Background: There is an assumption that fetus with restricted growth with an inappropriate intrauterine environment lies under stress. Although small-for-gestational-age (SGA) infants have higher mortality, difference in the outcome of SGA and appropriate-for-gestational-age (AGA) infants regarding respiratory morbidity is controversial. It seems that respiratory morbidities in SGA neonates is ...

Background: Androgenic hair loss (AGA) and alopecia areata (AA) are common conditions which sometimes are histologically difficult to differentiate. This study was conducted to detect differentiating features of these two disorders with IHC analysis of T-cell subsets in the inflammatory infiltrates of alopecia areata and androgenetic alopecia. Methods: This cr...

Androgenetic alopecia (AGA) is the most common type of progressive hair loss; however, its treatment remains limited in scope, thus driving need for alternative therapies restoration. The pathogenesis androgenetic not completely understood but involves disruption Wnt/β-catenin signaling pathway, resulting premature termination anagen growth phase follicles. This manifests clinically as transfor...