نتایج جستجو برای: aim

تعداد نتایج: 499916  

Journal: :Nature Medicine 1995

Journal: :Theoria 2021

In this paper I will consider relation between political environment and happiness, advocating the view according to which democracy represents a form of social life that positively affects happiness citizens. The subject my research be analysis basic psychological assumptions about influence society cultural on subjective feeling as well arguments could support democratic system most optimal f...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2002
Drew Pardoll

E since Paul Ehrlich introduced the term ‘‘magic bullet,’’ the exquisite capacity for specificity afforded by the immune system has always underpinned its appeal as a therapeutic weapon against cancer. The first clinical validation of this principle came in the form of mAb administration, which, after a decade of skepticism, produced therapeutic successes in breast cancer and B cell lymphomas. ...

Journal: :Canadian family physician Medecin de famille canadien 2014
Adrienne J Lindblad Mark Makowsky G Michael Allan

Evidence • Multiple cohort studies found PC patients did not achieve SMTs (ie, cholesterol, blood pressure [BP], glycated hemoglobin [HbA1c]). -Of 1706 patients with diabetes mellitus (DM), 7.3% achieved 3 targets (HbA1c < 7%, BP < 130/80 mm Hg, and cholesterol < 5.18 mmol/L)1; of 1701 Canadians, 24% had low-density lipoprotein (LDL) levels of < 2 mmol/L2; and of 3167 patients with coronary art...

Journal: :American journal of psychoanalysis 2008
Claudio Neri

This paper will present a series of predominantly clinical observations concerning the lengthy work a patient carries out, with the help of the analyst, in order to achieve greater personal authenticity. When this work is drawing to a close and the patient has gained a degree of authenticity, this authenticity remains within him, almost without his realizing it. The power of authenticity is ins...

Journal: :The Journal of clinical investigation 2007
Bryan C Barnhart M Celeste Simon

Increased cap-dependent mRNA translation rates are frequently observed in human cancers. Mechanistically, many human tumors often overexpress the cap binding protein eukaryotic translation initiation factor 4E (eIF4E), leading to enhanced translation of numerous tumor-promoting genes. In this issue of the JCI, Graff and colleagues describe potent antitumor effects using second-generation antise...

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