This study retrospectively investigated the prognostic significance of the preoperative albumin-globulin score (AGS) and albumin/globulin ratio (AGR) in esophageal squamous cell carcinoma (ESCC). A cohort of 458 newly diagnosed ESCC patients who underwent radical esophagectomy in Sun Yat-sen University Cancer Center (Guangzhou, China) between January 2006 and December 2010 were selected into th...

Sequential IgE-binding epitopes were identified on the molecular surface of Pis v 1 (2S albumin), 2 (11S globulin/legumin) and 3 (7S globulin/vicilin)—major allergens from pistachio (Pistacia vera) seeds—using Spot technique. They essentially consist hydrophilic electropositively charged residues well exposed allergens. Most epitopic regions do not coincide with putative N-glycosylation sites t...

BACKGROUND Pretreatment nutritional and immunological statuses play an indispensable role in predicting the outcome of patients with various types of malignancies. The purpose of this study is to evaluate the predictive value of albumin/globulin ratio (AGR) in overall survival (OS) and recurrence in patients with hepatocellular carcinoma (HCC) following radical hepatic carcinectomy. PATIENTS ...

As demonstrated by various investigators (Carter and Maclagan, 1946; Stillerman, 1948; Poulsen, 1949; Kalbak, 1951), the thymol reaction is positive in rheumatoid arthritis patients at a somewhat advanced and active stage of the disease. This positive reaction is assumed to be due to changes in the serum proteins. Patients with rheumatoid arthritis generally show marked changes in the serum pro...

Tetsuro Nishida Department of Internal Medicine, School of Medicine, Shinshu University (Prof.: Tadamasa Tozuka) In 60 cases of pulmonary tuberculosis treated with artificial pneumoperitoneum or with combination of pneumoperitoneum and chemotherapy, the relation between plasma protein fractions and clinical pictures was investigated, and following results were obtained. 1) In the plasma protein...

Background: The effects of aqueous extract of Fadogia agrestis stem at the doses of 18, 36, and 72 mg/kg body weight on alloxan-induced toxicity was investigated in Wistar rats. Methods: In total, 35 rats of both sexes (132.80±7.22g) were randomized into five groups (A-E): animals in group A received 0.5 ml of distilled water orally on daily basis for 15 days while the alloxanized rats in gr...

On hyperimmunization of rabbits with pneumococcal vaccine, increase in the content of gamma globulin and fall of albumin in the serum are produced. In such hyperimmunized rabbits, investigations of the plasma volume, albumin degradation, and the distribution of the albumin intra- and extravascularly were undertaken by Sterling's method employing rabbit albumin labelled with I(131). The investig...

To further evaluate thyroid function in patients with liver disease, we have measured total and free T3 and T4, thyroxine binding globulin, basal and thyrotropin releasing hormone-stimulated thyrotropin and thyroglobulin antibodies in 33 patients with liver cirrhosis, in 22 with chronic hepatitis and in 30 healthy controls. All the patients but one were clinically euthyroid. T3, FT3, T3/thyroxi...

1. Highly purified rabbit Type III pneumococcus anticarbohydrate proved to be homogeneous in the ultracentrifuge and its sedimentation constant, 7.0.10(-13), did not differ from that of the principal component of normal rabbit globulin or of immune rabbit globulin containing up to 50 per cent of anti-egg albumin. The molecular weight of antibody in the rabbit is therefore probably very close to...