background: some studies  in recent  years showed  that carotid  intima-media   thickness  (imt),  indicator  of  the presence  of atherosclerosis,  was higher  in non-alcoholic fatty  liver disease  (nafld)  in comparison  with  normal subjects.  they concluded  that  nafld  patients  may  be resulted  in more cardiovascular events. hence, we aimed to study the association of nafld and ischemi...

INTRODUCTION Mitochondrial dysfunction plays a central role in the general pathogenesis of non-alcoholic fatty liver disease (NAFLD), increasing the risk of developing steatosis and subsequent hepatocellular inflammation. We aimed to assess hepatic mitochondrial function by a non-invasive (13)C-methionine breath test (MeBT) in patients with histologically proven NAFLD. METHODS 118 NAFLD-patie...

The rising prevalence of childhood obesity in the past decades has made Non-Alcoholic Fatty Liver Disease (NAFLD) the most common cause of pediatric chronic liver disease worldwide. Currently, a growing body of evidence links NAFLD with cardiovascular disease (CVD) even at an early age. Data on the pediatric population have shown that NAFLD could represent an independent risk factor not only fo...

Non-alcoholic fatty liver disease (NAFLD) is a serious clinicopathological condition that recognized as the most frequent chronic disease, affecting 14–30% of world’s population. The prevalence NAFLD has rapidly grown and correlated with growth in obesity type 2 diabetes, among other factors. often results long-term complications including cardiovascular cirrhosis, fibrosis. This paper provides...

BACKGROUND Serum biomarkers of metabolic syndrome predict abnormal lung function in World Trade Center particulate matter (WTC-PM)-exposed Fire Department of New York (FDNY) rescue workers. In animal models, exposure to ambient PM induces non-alcoholic fatty liver disease (NAFLD), a well-known comorbidity of metabolic syndrome. YKL-40 is an inflammatory biomarker for both liver and lung disease...

Non-alcoholic fatty liver disease (NAFLD) is an important cause of liver disease burden across the world. By definition, although the histopathologic features of NAFLD are identical to that of alcoholic liver disease, its diagnosis requires absence of significant alcohol use and absence of other causes of chronic liver disease. We now know that NAFLD is not simply a disease of the Western world...

Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease globally, and it is expected to rise even further as a result of the increase in obesity and related risk factors. This short review summarises current evidence on the role of adipose tissue and insulin resistance in NAFLD and the interrelationship between NAFLD and the metabolic syndrome (MetS), considering cent...

Non-alcoholic fatty liver disease (NAFLD) covers a spectrum of disease ranging from simple steatosis (NAFL) to non-alcoholic steatohepatitis (NASH) and fibrosis. "Obese/Metabolic NAFLD" is closely associated with obesity and insulin resistance and therefore predisposes to type 2 diabetes and cardiovascular disease. NAFLD can also be caused by common genetic variants, the patatin-like phospholip...

Non-alcoholic fatty liver disease (NAFLD) is rapidly emerging as a leading etiology of chronic (CLD) in Asia. The increasing incidence NAFLD projected to drive surge NAFLD-related hepatocellular carcinoma (HCC). A notable characteristic NAFLD-HCC its capacity for development individuals without cirrhosis more than third patients. Most practice guidelines recommend biannual ultrasound screening ...

Background and Aims : It is now well established that non-alcoholic fatty liver disease (NAFLD) associated with a significant increase in the risk of adverse cardiovascular events. NAFLD-specific scores, considering traditional nontraditional factors, are needed to improve patient care. Liver fibrosis may be an integrative indicator burden cardiometabolic factors. also represent subclinical ath...