context viral hepatitis and the consumption of alcohol are recognized as important reasons for the development of liver disease throughout the world. it would also seem that chronic alcoholism causes more severe and rapid progression of liver disease in patients with chronic hepatitis c, leading to more frequent liver cirrhosis and hepatocellular carcinoma. evidence acquisition the data for thi...

introduction worldwide, chronic liver disease is a major cause of morbidity and mortality. causes of elevated serum alanine aminotransferase (alt) levels vary depending on the population under study. the aim of this study is to evaluate the frequency and causes of persistently elevated alt levels in patients of the gastroenterology (gi) clinics in ghaem and emam reza hospitals in mashhad, iran....

Background: The present study was undertaken to estimate the 5’-nucleotidase enzyme in chronic hepatitis B and alcoholics. The oxidative stress, antioxidants and their correlation with 5’-nucleotidase was also included in this study. Methods: The blood samples of 25 subjects (age and sex matched) each from group I (control), group II (alcoholic) and group III (chronic hepatitis B) was taken and...

BACKGROUND There have been very few studies evaluating the close association between excess iron and cirrhosis; however, cirrhosis could be regarded as an iron-loading disorder. OBJECTIVES In this study, the goal was to show the levels of the iron content in the liver tissue in certain types of cirrhosis. PATIENTS AND METHODS In this 7 year study (2008 - 2014), in 1000 explanted livers, the...

Alcoholic hepatitis (AH) is a type of acute-on-chronic liver failure and is the most severe form of alcoholic liver disease. AH occurs in patients with heavy alcohol abuse and underlying liver disease. In its severe form, AH carries a poor short-term prognosis. Although the existence of AH can be strongly suspected based on clinical and biochemical criteria, a definitive diagnosis requires a li...

Severe alcoholic hepatitis (sAH), defined by a modified discriminant function ≥32, is the most severe form of alcohol-induced liver disease and is associated with a 1-month mortality rate of around 30%. Corticosteroid treatment remains the only therapeutic option that improves short-term survival. Infectious complications, occurring in approximately 50% of patients, are the main causes of death...

Objectives: The aim of this study was to investigate the trends in research on non-alcoholic fatty liver disease (NAFLD) using Korean traditional medicine.Methods: This review included studies related treatment NAFLD, irrespective year publication. search terms were “nonalcoholic disease”, “non-alcoholic liver”, hepatitis”, “herb”, “herbal medicine”, “acupuncture”, and “traditional medicine”. a...