Pulmonary edema is a major cause of mortality due to acute lung injury (ALI). The involvement of protein kinase C-δ (PKC-δ) in ALI has been a controversial topic. Here we investigated PKC-δ function in ALI using PKC-δ knockout (KO) mice and PKC inhibitors. Our results indicated that although the ability to produce proinflammatory mediators in response to LPS injury in PKC-δ KO mice was similar ...

Abstract Background and Aims Acute kidney injury (AKI) acute liver (ALI) were associated with poor outcomes during hospitalization, respectively. However, the clinical outcome of AKI combined ALI (AKI-ALI) was still remains unknown. The current study aimed to describe incidences, risk factors, AKI-ALI. Method population included patients aged 18–99 years enough serum creatinine testing function...

Abstract The classical Khintchine–Groshev theorem is a generalization of Khintchine’s on simultaneous Diophantine approximation, from approximation points in ${\mathbb {R}}^m$ to systems linear forms {R}}^{nm}$. In this paper, we present an inhomogeneous version the that does not carry monotonicity assumption when $nm>2$. Our results bring theory almost line with homogeneous theory, wher...

PURPOSE OF REVIEW As incidence of acute lung injury (ALI) increases and case fatality decreases, long-term care of survivors is of public health importance. Previous studies demonstrate that these survivors are at risk for impairment in physical, cognitive and mental health. In this review, we will discuss recent studies that add to our knowledge of long-term outcomes after ALI and critical ill...

Bacterial infections of the lungs and abdomen are among the most common causes of sepsis. Abdominal peritonitis often results in acute lung injury (ALI). Recent reports demonstrate a potential benefit of parenteral vitamin C [ascorbic acid (AscA)] in the pathogenesis of sepsis. Therefore we examined the mechanisms of vitamin C supplementation in the setting of abdominal peritonitis-mediated ALI...

killifish (aphanius sophiae) of the cheshme-ali of damghan and shour river of eshteherd were studied and compared from morphological point of view. for morphometric studies, 34 truss morphometric measurements and  10 traditional  measurements  were made for each individual. nine meristic traits were counted. multi-variate analysis of variance (manova) revealed a significant different between va...

BACKGROUND The prognostic value of inflammation indexes in esophageal cancer has not been established. Recent studies have shown that the advanced lung cancer inflammation index (ALI) is a useful predictive factor. The purpose of the current study was to determine whether the ALI is useful for predicting long-term survival in patients with esophageal squamous cell carcinoma (ESCC). PATIENTS A...

THE ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) is characterized by rapid-onset, severe lung inflammation with massive influx of polymorphonuclear neutrophils (PMNs) into the lungs and injury to the alveolar capillary barrier and is associated with a high mortality rate. There is mounting evidence that matrix metalloproteinases (MMPs) contribute to the pathogenesis of ARDS. Most MMPs implicated ...

Acute limb ischemia (ALI) occurs due to abrupt interruption of arterial flow to an extremity, which may lead to loss of limb or life. ALI is typically caused by either a thrombotic or embolic arterial occlusion. Management strategies, which may not be mutually exclusive, include anticoagulation and observation, catheter-directed thrombolysis and/or surgical thrombectomy. The therapeutic choice ...