نتایج جستجو برای: alloimmunization

تعداد نتایج: 866  

Abstract Background and Objectives Human platelet antigens (HPAs) are polymorphic structures located on the membrane of platelets (PLTs). These antigens have important role in clinical situations like refractoriness to platelet transfusion which is the most important cause of transfusion related mortality and morbidity in patients by recurrent platelet transfusion. Alloimmunization against the...

Abstract Background and Objectives Blood transfusion related alloimmunization is common among patients receiving regular blood transfusion, especially thalassemia patients. In this study we aimed to find the prevalence of alloimmunization among patients of thalassemia.   Materials and Methods In this desciptional study, we screened 305 thalassemia patients (53.8% female and  46.2% male, age ...

Journal: :Haematologica 1998
P L Tazzari F Ricci C Tassi A Bontadini F Fruet R Conte

In our study we investigated the presence of anti-human platelet antigen (HPA) alloantibodies in a series of 10 beta-thalassemia major patients submitted for more than 10 years to periodic blood transfusions (every 2-3 weeks). We found that 2 out of the 10 patients developed anti-HPA2a + HPA1b and anti-HPA2b antibodies. Our results highlight that HPA alloimmunization in multitransfused patients...

Journal: :International Journal of Blood Transfusion and Immunohematology 2011

Journal: :International Journal of Blood Research and Disorders 2020

2017
Dimel K. Bhuva Jitendra H. Vachhani

INTRODUCTION Repeated blood transfusions can result in the production of alloantibodies against one or more red cell antigens, which complicates subsequent transfusions. Aims: The study was done to find incidence of various red cell alloantibodies; to determine the type of alloantibody; to identify the factors such as frequency of transfusion, splenectomy status, donor ethnicity and gender and ...

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