An allometric height-mass exponent γ gives an approximative power-law relation 〈M〉 ∝ H between the average mass 〈M〉 and the height H , for a sample of individuals. The individuals in the present study are humans but could be any biological organism. The sampling can be for a specific age of the individuals or for an age-interval. The body-mass index (BMI) is often used for practical purposes wh...

Theoretical models of allometric scaling provide frameworks for understanding and predicting how and why the morphology and function of organisms vary with scale. It remains unclear, however, if the predictions of 'universal' scaling models for vascular plants hold across diverse species in variable environments. Phenomena such as competition and disturbance may drive allometric scaling relatio...

UNLABELLED Virions vary in size by at least 4 orders of magnitude, yet the evolutionary forces responsible for this enormous diversity are unknown. We document a significant allometric relationship, with an exponent of approximately 1.5, between the genome length and virion volume of viruses and find that this relationship is not due to geometric constraints. Notably, this allometric relationsh...

The appropriateness of relying on the coefficient of determination (r) as a statistical metric for judging the predictability of human clearance (CL) based on interspecies animal data was assessed. An explicit mathematical expression was derived for r as a function of species body weight and the corresponding measured value of CL. The derived mathematical function demonstrated that r is numeric...

LINKED ARTICLES This article is commented on in the editorial by Holford NHG and Anderson BJ. Why standards are useful for predicting doses. Br J Clin Pharmacol 2017; 83: 685-7. doi: 10.1111/bcp.13230 AIM: When different models for weight and age are used in paediatric pharmacokinetic studies it is difficult to compare parameters between studies or perform model-based meta-analyses. This study ...

Historically, allometric equations relate organismal traits, such as metabolic rate, individual growth rate, and lifespan, to body mass. Similarly, Boltzmann or Q(10) factors are used to relate many organismal traits to body temperature. Allometric equations and Boltzmann factors are being applied increasingly to higher levels of biological organization in an attempt to describe aggregate prope...

In multivariate regression, interest lies on how the response vector depends a set of covariates. A regression model is proposed where covariates explain variation in only direction first principal component axis. This not parsimonious, but it provides an easy interpretation allometric growth studies log-transformed data corresponds to constants growth. The naturally generalizes two–group exten...

BACKGROUND Chemical restraint is of great importance in the clinical practice of wildlife animals. In such, interspecific allometric scaling proposes pharmacological doses to a wide range of species, based on previously known doses for domestic animals and the target animal's body mass. The objective was to compare chemical restraint responses in the greater rhea (Rhea americana) with conventio...