Amniotic fluid at 15-20 weeks contains high concentrations of microvillar enzymes which serve as markers for the prenatal diagnosis of cystic fibrosis. We found that these enzymes were mostly bound to amniotic fluid particulate fraction which eluted in the void volume on Sepharose 6B chromatography and precipitated in ultracentrifugation at 100,000g. Electron microscopy showed that the particul...

PURPOSE To compare the safety and efficacy of human preserved amniotic membrane (AM) in the trabeculectomy for treatment of primary open-angle glaucoma. METHODS A prospective, randomized clinical trial compared primary trabeculectomy with amniotic membrane (study group) and without amniotic membrane (control group) in the treatment of the glaucoma. Intraocular pressure (IOP), number of glauco...

BACKGROUND Mooren's ulcer is a severe ulcerative inflammation of the cornea. The exact pathogenesis remains unclear. Therefore many therapies of Mooren's ulcer are recommended in literature. To shed more light on the ongoing question of optimal treatment of severe progressive Mooren's ulcer, we here report on a retrospective case series of patients treated with systemic immunosuppressive therap...

Cetuximab (Erbitux) is an antiepidermal growth factor receptor (EGFR) monoclonal antibody that has been shown to delay the progression of metastatic colorectal cancer. The cutaneous side effects of cetuximab resulting from its effects on normal epidermal cells are well established. Periocular side effects, including blepharitis, trichomegaly, dry eye and conjunctivitis, have also been reported....

The purpose of this study is to analyze clinical experience about the effects of human amniotic membrane transplantation in eyes with neurotrophic ulcers. In 11 eyes the application of amniotic membrane was performed since January 1999 because of neurotrophic ulcers. The follow up period was longer than 12 months: 19.7+/-6.0 months. The average healing period after the surgery was 1.6+/-0.6 wee...

Purpose:Human amniotic fluid contains several growth factors and hyaluronic acid. It has positive effect in healing the tendon, nerve bone injuries. Human membrane effects on is also used for skin burns complex wounds. We hypothesized that human have stimulating fracture healing. The aim of this study to investigate rat tibial model.

M. Parthasarathy, R. Sasikala, P. Gunasekaran and J. Raja Dept. of Biotechnology, Vel Sri Ranga Sanku College of Arts and Science, Avadi, Chennai-62 Dept. of Biological Control, King Institute of Preventive Medicine and Research, Guindy, Chennai-32, India [email protected]*; +91 9677299256 ______________________________________________________________________________________________ Abstrac...

Vertical root fracture(VRF) is one of the common reasons for extraction of endodontically treated teeth. Though many options of saving such teeth were available, they were not of much success. Therefore the objective of this article is to discuss one such case. A 50 year old male patient reported with Vertical root fracture and 15 mm of periodontal probing depth in the distal aspect of 14. Radi...

Ophthalmol. 1998;116:372-373. 22. Tseng SC, Prabhasawat P, Lee SH. Amniotic membrane transplantation for conjunctival surface reconstruction. Am J Ophthalmol. 1997; 124:765-774. 23. Shields CL, Shields JA, Armstrong T. Management of conjunctival and corneal melanoma with combined surgical excision, amniotic membrane allograft, and topical chemotherapy. Am J Ophthalmol. 2001;132:576-578. 24. Par...

Non healing wounds present a significant social and economic burden. Chronic non healing wounds are estimated to affect as many as 1-2% of individuals during their lifetime, and account for billions of dollars of expense annually on both a national and global basis. Our purpose is to describe the use of a novel dehydrated amniotic membrane allograft (EpiFix(®) ; MiMedx Group, Inc., Kennesaw, GA...