In this work we are studying whether calcium phosphate deposition (CPD) during vascular calcification is a passive or a cell-mediated mechanism. Passive CPD was studied in fixed vascular smooth muscle cells (VSMC), which calcify faster than live cells in the presence of 1.8 mM Ca²(+) and 2 mM P(i). CPD seems to be a cell-independent process that depends on the concentration of calcium, phosphat...

Cows’ milk contains inorganic calcium phosphate as a tightly-bound component of the casein micelles. The composition and chemical properties of this calcium phosphate have been studied for many years. Although the Ca/P ratio is similar to that found in hydroxyapatite, the use of other methods of characterization is desirable, since the various crystalline and amorphous forms of inorganic calciu...

UNLABELLED The development of bioactive phosphate-based glasses is essential in biomaterials science, and especially for bone substitution applications. In this context, the preparation of amorphous calcium-phosphorus hydroxide/oxide monoliths at low temperature is a key challenge for being able to develop novel hybrid materials for these applications. We herein report for the first time the sy...

AIM To determine if the addition of inert fillers to a bioactive dental restorative composite material affects its degree of conversion (DC), polymerization shrinkage (PS), and microhardness (HV). METHODS Three amorphous calcium phosphate (ACP)-based composite resins: without added fillers (0-ACP), with 10% of barium-glass fillers (Ba-ACP), and with 10% of silica fillers (Si-ACP), as well as ...

The aim of this in vitro study was to compare the shear bond strength (SBS) and failure modes of a conventional resin-based composite with a recently developed amorphous calcium phosphate (ACP)-containing orthodontic composite system. Forty freshly extracted human maxillary premolar teeth were randomly divided into two equal groups. Conventional composite (group 1; Transbond-XT; 3M Unitek) and ...

The feasibility of calcium carbonate cements involving the recrystallisation of metastable calcium carbonate varieties has been demonstrated. Calcium carbonate cement compositions presented in this paper can be prepared straightforwardly by simply mixing water (liquid phase) with two calcium carbonate phases (solid phase) which can be easily obtained by precipitation. An original cement composi...

We are familiar with large highly-ordered single crystals, such as those used in the semiconductor industry. There the crystalline ordering in the silicon crystals extends for billions and more lattice spacings. As a result, X-ray diffraction (XRD) patterns of these crystals have sharp Bragg peaks. We are also familiar with liquids, where the molecules have a local structure that is very differ...

Chlorapatite can be considered a potential biomaterial for orthopaedic applications. Its use as plasma-sprayed coating could be of interest considering its thermal properties and particularly its ability to melt without decomposition unlike hydroxyapatite. Chlorapatite (ClA) was synthesized by a high-temperature ion exchange reaction starting from commercial stoichiometric hydroxyapatites (HA)....