Jones, N. F., Barraclough, M. A., Barnes, N., and Cottom, D. G. (1972). Archives of Disease in Childhood, 47, 794. Nephrogenic diabetes insipidus: effects of 3,5, cyclic-adenosine monophosphate. In view of the evidence that the actions of vasopressin are mediated by the release of adenosine 3,5, cyclic monophosphate ('cyclic-AMP'), the effects of this nucleotide were studied in 3 children with ...

in more recent years, it has become increasingly recognized that r&d; (research and development) is a key driver of economic growth, a source of innovation and change, and as such stimulates improvements in productivity and economic competitiveness. it is closely associated with knowledge and flexibility, two factors that have gained new significance as a source of competitiveness in an increas...

In intrusion detection systems, classifiers still suffer from several drawbacks such as data dimensionality and dominance, different network feature types, impact on the classification. this paper two significant enhancements are presented to solve these drawbacks. The first enhancement is an improved selection using sequential backward search information gain. This, in turn, extracts valuable ...

Abstract. Nitryl chloride (ClNO2), an important precursor of Cl atoms, significantly affects atmospheric oxidation capacity and O3 formation. However, sources ClNO2 in inland China have not been fully elucidated. In this work, laboratory experiments were conducted to investigate heterogeneous reactions N2O5 with eight saline mineral dust samples collected from different regions China, substanti...

Ampelopsin (AMP), a major bioactive constituent of Ampelopsis grossedentata, exerts a number of biological effects. In this study, we investigated its anti-cancer activity in human breast cancer cell lines, and explored the underlying mechanism of this action. Our results showed that treatment with AMP dose-dependently inhibited cell viability and induced apoptosis in MCF-7 and MDA-MB-231 breas...

UV-induced photochemical crosslinking is a powerful approach that can be used for the identification of specific interactions involving nucleic acid-protein and nucleic acid-nucleic acid complexes. 8-AzidoATP (8-N(3)ATP) is a photoaffinity-labeling agent which has been widely used to elucidate the ATP binding site of a variety of proteins. However, its true potential as a photoactivatable nucle...

Abstract. The isotopic composition of nitrogen and oxygen in dioxide (NO2) potentially carries a wealth information about the dynamics oxides (NOx = nitric oxide (NO) + NO2) chemistry atmosphere. While isotopes NO2 are subtle indicators NOx emissions chemistry, believed to reflect only O3 / VOC chemical regime different atmospheric environments. In order access this potential tracer tropospheri...

The localization and chemical characteristics of two Golgi integral membrane proteins (GIMPs) have been studied using monoclonal antibodies. The two proteins are segregated in different parts of the Golgi system and whereas GIMPc(130 kD) is located in the cis and medial cisternae, GIMPt (100 kD) is confined in the trans-most cisterna and trans-tubular network. Both GIMPs are glycoproteins that ...

AMP-activated protein kinase (AMPK) acts as a cellular energy sensor: it responds to an increase in AMP concentration ([AMP]) or the AMP-to-ATP ratio (AMP/ATP). Metformin and phenformin, which are biguanides, have been reported to increase AMPK activity without increasing AMP/ATP. This study tests the hypothesis that these biguanides increase AMPK activity in the heart by increasing cytosolic [...

A multi-lane free flow (MLFF) toll collection system installed on a simplified gantry requires compact cameras for supervising enforcement. Because these compact cameras have low image resolution, it is also necessary to develop vehicle license plate recognition technology that uses dynamic image processing. Mitsubishi Heavy Industries, Ltd. (MHI) has developed three technologies based on the c...