In this paper, we propose a novel 2D plenoptic function called “acentric panorama view (APV).” This novel 2D plenoptic function samples the panorama scenes without oversampling or undersampling. A single APV can be accelerated by view culling and list-priority rendering algorithm. Multiple APVs with special fields of view, 45◦, 60◦, 90◦, and 120◦, can be integrated into a larger configuration c...

PURPOSE OF REVIEW This review discusses the use of the inhibitory quotient in light of therapeutic drug monitoring of antiretroviral drugs. The inhibitory quotient is a parameter that combines viral resistance data with drug exposure data, and has its main role in therapeutic drug monitoring of protease inhibitors in experienced patients. Data from recent clinical studies investigating inhibito...

This talk describes some of the precision electroweak measurements from around the world, namely those related to the Z and W bosons, the top quark mass, sin 2 θ W at NuTeV, and three other fundamental measurements: α −1 (m 2 Z), (g − 2) µ at the E821 BNL experiment as well as the atomic parity violation (APV) measurement for the Cesium atom. These and other measurements are set in the context ...

We present a concise review of the status of the Standard Model and of the search for new physics. The results of the electroweak precision tests as well as of the searches for the Higgs boson and for new particles performed at LEP and SLC are now available in nearly final form. Taken together with the measurements of m t , m W and the searches for new physics at the Tevatron, and with some oth...

In 1978, Prescott et al. [1] showed that parity-violating could be observed in neutral currents by measuring the asymmetry APV = (σR − σL)(σR + σL) in the deep inelastic scattering (DIS) of polarized electrons from deuterium. By extending the kinematic range, the same group later published results that were able to exclude alternative theories to the Standard Model that were considered reasonab...

The E158 experiment at SLAC has made the first measurement of parity violation in electron-electron (Møller) scattering. We report a preliminary result using 50% of the accumulated data sample for the right-left parity-violating cross-section asymmetry (APV ) in the elastic scattering of 45 and 48 GeV polarized electron beams with unpolarized electrons in a liquid hydrogen target. We find APV =...

HIV drug resistance continues to emerge; consequently, there is an urgent need to develop next generation antiretroviral therapeutics.1 Here we report on the structural and kinetic effects of an HIV protease drug resistant variant with the double mutations Gly48Thr and Leu89Met (PRG48T/L89M), without the stabilizing mutations Gln7Lys, Leu33Ile, and Leu63Ile. Kinetic analyses reveal that PRG48T/...

The restriction of a small molecule's motion on binding to a protein causes a loss of configurational entropy, and thus a penalty in binding affinity. Some energy models used in computer-aided ligand design neglect this entropic penalty, whereas others account for it based on an expected drop in the number of accessible rotamers upon binding. However, the validity of the physical assumptions un...

We compared 2 rules-based genotype interpretation systems and real or virtual phenotype through a retrospective analysis of a prospective trial. Genotypes were determined with VircoGEN II (VIRCO) and were interpreted with either RetroGram 1.4 or TRUGENE HIV-1 (guidelines 3.0) or original virtual phenotype (Virtual Phenotype; VIRCO), as available in the year 2000. Among 188 human immunodeficienc...

We derive a wave-averaged potential vorticity equation describing the evolution of strongly stratified, rapidly rotating quasi-geostrophic (QG) flow in a field of inertia-gravity internal waves. The derivation relies on a multiple-time-scale asymptotic expansion of the Eulerian Boussinesq equations. Our result confirms and extends the theory of Bühler & McIntyre (J. Fluid Mech., vol. 354, 1998,...