We present a graphical user interface which facilitates the deenition of anatomical boundaries and landmarks for automated model-based segmentation and analysis using 3D Active Shape Models (ASMs). ASMs provide a statistically-based approach to automatic segmentation which is completely general in terms of both imaging modalities and the anatomical objects of interest. Further, the ASM guarante...

In vitro – in vivo correlation (IVIVC) allows prediction of drug deposition from a nasally inhaled based on measurements. measurements include physical particle characterization and, more recently, studies using anatomical models. Currently, there is lack IVIVC for models, especially patterns various nasal cavity regions. Therefore, improvement and measurement methods knowledge about mechanisms...

Acquaintance with the different anatomical variations of the arterial supply of the gallbladder is of great importance in hepatobiliary surgical procedures. A rare variation of the hepatobiliary arterial system was found during anatomical dissection of a female Iranian cadaver. Two cystic arteries were present, the first arising directly from the right hepatic artery and the second from the gas...

As human brain development proceeds, there are complex changes in size and shape, most notably in the developing forebrain. Molecular technologies enable us to characterise the gene expression patterns that underlie these changes. To interpret these patterns the location of expression must be identified and, often, gene expression patterns compared for several genes or across several developmen...

The 2- and 3-dimensional (3D) anatomy and the morphometric properties of the paranasal sinuses of the foal have received little or no attention in the literature. The aim of this study was to obtain details of the paranasal sinuses using multiplane CT imaging to create 3D models and to determine morphological and morphometric data for the sinuses using the 3D models. The heads of five female fo...

Although the contribution to anatomical illustration by Vesalius and his followers has received much attention, less credit has been given to Veslingius and particularly Fabricius. By 1600, Fabricius had amassed more than 300 paintings that together made the Tabulae Pictae, a great atlas of anatomy that was highly admired by his contemporaries. Many of his new observations were incorporated int...

Primljeno (Received): 2011-10-10 Prihvaćeno (Accepted): 2012-02-28 Original scientific paper In today's medicine, especially in the field of orthopedic surgery, it is very important to use geometrically accurate and anatomically correct geometrical models of human bones for the pre-operative planning and implants creation. In order to create such models, two new methods for geometrical modeling...

  The anterior cruciate ligament (ACL) is composed of two bundles, which work together to provide both antero-posterior and rotatory stability of the knee. Understanding the anatomy and function of the ACL plays a key role in management of patients with ACL injury. Anatomic ACL reconstruction aims to restore the function of the native ACL. Femoral and tibial tunnels should be placed in their an...

Fine-scale anatomical structures in the heart may play an important role in sustaining cardiac arrhythmias. However, the extent of this role and how it may differ between species are not fully understood. In this study we used computational modelling to assess the impact of anatomy upon arrhythmia maintenance in the rabbit ventricles. Specifically, we quantified the dynamics of excitation wavef...