The pages of this journal are full of remarkable stories of scientists working with extraordinary and commonplace creatures to understand how these species survive and interact with their environment. None of these studies could have been undertaken without the contributions of the central protagonists themselves, and in the fields of biomedical research and ecotoxicology, large numbers of vert...

ECR Spotlight is a series of interviews with early-career authors from selection papers published in Journal Experimental Biology and aims to promote not only the diversity researchers (ECRs) working experimental biology during our centenary year, but also huge variety animals physiological systems that are essential for ‘comparative’ approach. Glenna Clifton an author on ‘ The bumpy road ahead...

In recent years the treatment of rheumatoid arthritis (RA) has changed considerably with the advent of novel biologic agents that target cytokines such as TNF. The impact on clinical practice has been considerable with achievement of high hurdle endpoints and reduced articular damage. Unfortunately, remission that is long lasting is rarely achieved and almost never reached in the absence of chr...

The past two decades have witnessed an evolving understanding of the mitochondrial genome's (mtDNA) role in basic biology and disease. From the recognition that mutations in mtDNA can be responsible for human disease to recent efforts showing that mtDNA mutations accumulate over time and may be responsible for some phenotypes of aging, the field of mitochondrial genetics has greatly benefited f...

A major challenge of invasion biology lies in the development of a predictive understanding of invasion processes. Attempts to identify the proximate causes of invasion success or to predict rates of spread seldom emphasize behavioral characteristics. Recent experimental work, however, illustrates that insight into the proximate causes of animal invasions often hinges on a careful assessment of...

Molecular biology has contributed in a wide and profound way to our current knowledge of the structure of pathogens, how they replicate in a host animal and how they may cause disease. This molecular knowledge has been harnessed in practical ways to improve the sensitivity, specificity and safety of methods to identify infected animals and characterise the causative infectious agents. It has al...

In the text, as well as on the title-page, of this book Psychotherapy is thus defined: "Treatment that attempts to improve the condition of a human being by means of influences that are brought to bear upon his mind (psyche)." This definition is characteristic of the book or, as one had better say, of the wisdom and common sense of its author. Dr. Barker emphasizes the necessity of a full work-...

Abstract Dr. Barrangou’s research focuses on the biology and genetics of CRISPR-Cas immune systems in bacteria. Using microbiology, molecular genomics approaches, he investigates use to generate novel tools for manipulation industrially relevant organisms food biotechnological applications. Barrangou talk will be an update CRISPR technology its many applications with select examples related ani...

Roundworms of the Nematoda comprise one of the largest animal phyla on Earth (1). They inhabit diverse terrestrial and aquatic niches through adaptations of a spectrum of trophic groups, including parasites that threaten human, animal and crop plant health. The most well-known nematode, Caenorhabditis elegans, is a native soil-dwelling microbivore that has emerged as a premier model for animal ...