Endocrine-disrupting chemicals (EDC) are an inevitable environmental pollutant due to their wide range of applications in the industrial sector. Deliberate or unkempt disposal materials containing EDCs has also significantly contributed its ecological exposure. Several natural and synthetic recognized which at low doses capable eliciting abnormal responses body, this is a threat life for both h...

Normal somatic growth requires that both the thyroid hormone axis and GH axis be intact. Thyroid hormone stimulates GH secretion, and many thyroid hormone actions on the insulin-like growth factor (IGF) system can be explained by this mechanism. We have previously described distinct changes in IGF binding protein (IGFBP) expression in experimental hypothyroidism in the rat; these changes could ...