نتایج جستجو برای: animal testing alternatives
تعداد نتایج: 580515 فیلتر نتایج به سال:
Abstract: Aim: The present work aimed at the utilization of alternative animal models in research. Background: Animal from a long time played an important role drug and vaccine development. However, due to limitation like logistic, scientific regulatory need became hour. Materials Methods: Alternative are strategies which basically substitute live models. During COVID-19 ongoing pandemic fast, ...
In 1959, William Russell and Rex Burch published the seminal book, The Principles of Humane Experimental Technique, which emphasized reduction, refinement, and replacement of animal use, principles which have since been referred to as the ‘‘3 Rs’’. These principles encouraged researchers to work to reduce the number of animals used in experiments to the minimum considered necessary, refine or l...
Registration, Evaluation, Authorization, and Restriction of Chemicals (REACH) is a new chemicals regulation law in the European Union (EU). The law is supplemented by tens of thousands of pages of guidance documents, and the implementation of REACH is still a work in progress. Requirements for chemical testing are based on the annual volume of a chemical or 'substance' that is produced or impor...
An Expert Meeting on The Current Scientific and Legal Status of Alternative Methods to the LD50 Test for Botulinum Neurotoxin (BoNT) Potency Testing was organised by the Centre for Documentation and Evaluation of Alternatives to Animal Experiments (ZEBET) at the Federal Institute for Risk Assessment (BfR), and took place on 27–28 April 2009, in Berlin, Germany. The goal of ZEBET is to promote p...
Abstract Context Cultural competency is a cornerstone of patient-centered health care. Religious doctrines may define appropriate consumption or use certain animals and forbid others. Many medications contain ingredients that are animal-derived; these be unacceptable to individual patients within the context their religious beliefs lifestyle choices. Knowledge animal-derived as component cultur...
E-cigarettes have become within only one decade an important commodity, changing the market of the most mass-killing commercial product. While a few years ago estimates suggested that in the course of the 21st century one billion people would die prematurely from tobacco consumption, e-cigarettes continuously gaining popularity promise 10-30fold lower health effects, possibly strongly changing ...
This glossary was developed to provide technical references to support work in the field of the alternatives to animal testing. It was compiled from various existing reference documents coming from different sources and is meant to be a point of reference on alternatives to animal testing. Giving the ever-increasing number of alternative test methods and approaches being developed over the last...
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