Artemisinin 1, dihydro-epideoxyarteannuin B 2 and deoxyartemisinin 3 were isolated from the sequiterpene lactone-enriched fraction obtained from the crude ethanolic extract of Artemisia annua L. These compounds were tested on ethanol and indomethacin-induced ulcer models. Compound 1 did not afford cytoprotection under the experimental models tested. Only compounds 2 and 3 decreased the ulcerati...

Malaria is a life-threatening disease affecting a major portion of the world’s population with considerable loss of human life. Artemisinin, isolated from Artemisia annua, its oiland water-soluble derivatives, and other known antimalarials are recommended for artemisinin combination therapy by the World Health Organization. We have established a method for the stereoselective synthesis of bethe...

Sweet wormwood (Artemisia annua L.) valorization is gaining importance due to the presence of health-promoting bioactive compound, artemisinin. Considering wide possible application artemisinin drug formulations, new, greener technologies in their production are welcome. In this study, was extracted from A. leaves using green extraction (ultrasound-assisted extraction, supercritical CO2 deep eu...