نتایج جستجو برای: anti neutrophil cytoplasmic antibody

تعداد نتایج: 585343  

Journal: :Investigative ophthalmology & visual science 2003
David Stempel Hallie Sandusky Kirsten Lampi Marianne Cilluffo Joe Horwitz Jonathan Braun Lee Goodglick Lynn K Gordon

PURPOSE Perineuclear anti-neutrophil cytoplasmic antibody (pANCA), a marker antibody present in 12% of patients with anterior uveitis, recognizes cytoplasmic antigens in the nonpigmented ciliary body epithelium, a probable site of immunologic reactivity in this inflammatory disease. In this study, a recombinantly isolated pANCA monoclonal antibody was used to identify the corresponding antigeni...

2018
Jeong-Hoon Lim Sang Yup Lee Hyejin Cheon Yong-Lim Kim

A healthy 42-year-old woman presented proteinuria and hematuria on regular medical check-up two years ago. Her other laboratory examinations did not show any abnormal findings, including renal function, anti-neutrophil antibody, anti-neutrophil cytoplasmic antibody, C3, C4, or immunoglobulin. Her blood pressure was also normal. Because flank pain had developed, color Doppler ultrasound of the k...

Journal: :Journal of Immunology 2023

Abstract Anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV) is a rare autoimmune disease with suboptimal treatment options which contribute to morbidity and mortality. The characteristic pathological feature severe inflammation induced by neutrophils causes life threatening damage the small blood vessels of kidney. Neutrophil activity influenced microbial metabolites, inclu...

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