33 The Olive Baboon (Papio anubis): A Potential Animal Model to Study the Function of Human Leukocyte Antigen-G (HLA-G) Langat, D.K. (Kansas City, Kans./Nairobi); Morales, P.J. (Kansas City, Kans.); Fazleabas, A.T. (Chicago, Ill.); Mwenda, J.M. (Nairobi); Hunt, J.S. (Kansas City, Kans.) 36 The Prevalence of Anti-Phospholipid Antibodies in a Selected Population of Kenyan Women and Development of...

Background: Catastrophic Antiphospholipid syndrome (CAPS) is a scarcely understood entity with a high mortality approaching 50%The rapid deterioration is triggered by a deadly cytokine storm, which is difficult to recognize and almost impossible to treat in time. Various regimens have been advocated, which include administration of monoclonal anti-phospholipid antibodies and pulses of high dose...

33 The Olive Baboon (Papio anubis): A Potential Animal Model to Study the Function of Human Leukocyte Antigen-G (HLA-G) Langat, D.K. (Kansas City, Kans./Nairobi); Morales, P.J. (Kansas City, Kans.); Fazleabas, A.T. (Chicago, Ill.); Mwenda, J.M. (Nairobi); Hunt, J.S. (Kansas City, Kans.) 36 The Prevalence of Anti-Phospholipid Antibodies in a Selected Population of Kenyan Women and Development of...

The antiphospholipid syndrome is a thrombophilic condition marked by antibodies that recognize anionic phospholipid-protein cofactor complexes. We recently reported that exposure to IgG fractions from antiphospholipid patients reduces the level of annexin-V, a phospholipid-binding anticoagulant protein, on cultured trophoblasts and endothelial cells and accelerates coagulation of plasma exposed...

BACKGROUND Antibodies against cardiolipin and phosphatidylserine (anti-CL and anti-PS) are associated with thrombosis. In contrast, we determined that IgM antibodies against oxidized CL and PS (OxCL and OxPS) and phosphorylcholine (anti-PC) could be protection markers for cardiovascular disease (CVD). METHODS 226 individuals with established hypertension (diastolic pressure>95 mmHg) from the ...

The effect of anti-follicular stimulating hormone (FSH) on testicular lipid and the specific activity of testicular enzymes of the isocitrate dehydrogenase (ICDH), pyruvate/malate dehydrogenase (MDH) and malic enzyme involved in lipogenesis were studied in mature bonnet monkeys, Macaca radiata. Immunization of monkey with anti-FSH for 24 days did not produce any significant changes in the body ...

Warfarin induced skin necrosis (WISN) is a rare but important side effect of warfarin. Early diagnosis may lessen the amount of permanent tissue damage and can prevent progression to full thickness skin necrosis. So, physicians should be aware of such a complication. Screening for protein C or S or anti-thrombin deficiencies, or presence of anti-phospholipid antibodies before beginning warfarin...

the measurement of anti-streptokinase antibodies can distinguish the patients who may benefit from streptokinase and those who should be treated with some other thrombolytic regimen. neutralising titration test is a commonly used classical assay for measuring anti-streptokinase antibodies and in this assay the ability of anti-streptokinase antibodies in patients' sera in preventing the lytic ef...