Bacteriocins are proteinaceous antibacterial compounds, produced by diverse bacteria, which have been successfully used as: (i) food biopreservative; (ii) anti-biofilm agents; and (iii) additives or alternatives to the currently existing antibiotics, to minimize the risk of emergence of resistant strains. However, there are several limitations that challenge the use of bacteriocins as biopreser...

Accepted on 26 th December 2016, Published online on 27 th January 2017 _____________________________________________________________________________ ABSTRACT During the present investigation, a new series of 3,6-disubstituted[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives (3) were synthesized by refluxing a mixture of 3-substituted-4-amino-5-mercapto-1,2,4triazoles with substituted anilin...

Andrographis paniculata nees (Acanthaceae) is a medicinal plant traditionally used for the treatment of anti-inflammatory, antibacterial, antioxidant, antiparasitic, antispasmodic, antidiabatic, anti carcinogenic, antipyretic, antidiarrhoeal, hepatoprotective, nematocidal, antiHIV and several infectious diseases ranging from malaria to dysentery. The plant is widely used in ayurvedic and homeop...

In this study, the ability of porous silicon nanoparticles (PSi NPs) to entrap and deliver nitric oxide (NO) as an effective antibacterial agent is tested against different Gram-positive and Gram-negative bacteria. NO was entrapped inside PSi NPs functionalized by means of the thermal hydrocarbonization (THC) process. Subsequent reduction of nitrite in the presence of d-glucose led to the produ...

Propolis is one of the complex, but valuable, bio-sources for discovering therapeutic compounds. Diterpenes are organic compounds composed of four isoprene units and are known for their biological and pharmacological characteristics, such as antibacterial, anticancer, and anti-inflammatory activities. Recently, advancements have been made in the development of antibacterial and anticancer leads...

Ethanolic extract of roots and aerial parts of Achyranthes aspera was investigated for its antibacterial activity against Bacillus subtilis, Bacillus pumilus, and Proteus vulgaris and anti fungal activity against Cryptococcus neoformans, Aspergillus flavus at 100 mg/disc using diffusion method. The comparative studies shown that ethanolic extract of roots and aerial parts of Achyranthes aspera ...

Protease inhibitors were extracted from the seeds of Lavatera cashmeriana Camb by ammonium sulphate precipitation and purified by chromatography on DEAE-cellulose and Sephadex G-100 column. The bound protein eluted into four major peaks which we named as LC-pi I, II, III and IV, all showing strong anti protease activity against trypsin, chymotrypsin and elastase. LC-pi I was screened for antiba...

Anti-acne herbal formulations are used for the treatment of acne vulgaris with the added advantage of not producing adverse effects unlike synthetic drugs. Phytoconstituents present in methanolic extracts of Camellia sinensis (CSME), Glycyrrhiza glabra (GGME) and Calendula officinalis (COME) have antibacterial and antioxidant properties. Validated HPTLC fingerprinting confirmed the presence of ...