BACKGROUND Antibiotic residues can cause antibiotic resistance in livestock and their food safety-related issues have increased the consumer demand for products lacking these residues. Hence, developing safe and effective antibiotic alternatives is important to the animal feed industry. With their strong antibacterial actions, antimicrobial peptides have potential as antibiotic alternatives. ...

Triclosan (TCS) has been widely used as an antibacterial and antifungal agent in household cleaning and personal care products. The widespread use of TCS in the cleaning products poses a potential risk to the ecological system and human health due to its release into sediments, wastewater and ground water resources causing chronic toxicity to aquatic organisms. Therefore, it is necessary to dev...

Microorganisms are well-known producers of a wide variety of bioactive compounds that are utilized not only for their primary metabolism but also for other purposes such as defense, detoxification, or communication with other micro- and macro-organisms. Natural products containing a 'decalin ring' occur often in microorganisms. They exhibit diverse and remarkable biological activities, includin...

Plant essential oils are potential source of antimicrobials of natural origin. Essential oils and extracts obtained from many plants have recently gained a great popularity and scientific interest. Consumer demand for natural preservatives has increased, whereas the safety aspect of chemical additives has been questioned. The plant oil has been reported to have antibacterial, antifungal, antivi...

Phytochemical studies on the ethanolic extract of the roots of Buxus sempervirens of Turkish origin have resulted in the isolation of two new triterpenoidal alkaloids, (+)-16a, 31-diacetylbuxadine (1), (-)-Nb-demethylcyclomikuranine (2) along with three known natural products, (-)-cyclomikuranine (3), (-)-cyclobuxophylline-K (4) and (+)-buxaquamarine (5) isolated for the first time from this sp...

BACKGROUND The current trend globally is the utilization of natural products as therapeutic agents given its minimum side effects. The leaves of Stevia contain several active ingredient compounds such as rebaudioside. Stevia extract have been used for many purposes. Active oxygen radicals can induce base modifications, DNA breakage, and intracellular protein crosslink's. This study was done to ...

Penicillins may be regarded as acylation products of 6-aminopenicillanic acid (Figure 1). This bicyclic dipeptide results from cyclization of L-Cysteinyl-L-valine (1) and is loosed into the culture medium in good yield when a strain of Penicillium chrysogenurn (W.51.20) is cultured in the absence of side chain precursors suitable for acylation at the 6-amino grouping (2). With the attainment of...

Flavonoids are ubiquitous in photosynthesising cells and are commonly found in fruit, vegetables, nuts, seeds, stems, flowers, tea, wine, propolis and honey. For centuries, preparations containing these compounds as the principal physiologically active constituents have been used to treat human diseases. Increasingly, this class of natural products is becoming the subject of anti-infective rese...

Background: Various herbal products are being tried to treat common ailments. Such a trend is witnessed in dentistry also. gall extract of Quercus infectoria has been found to possess antibacterial properties against some common oral pathogens. Aim: to assess the antibacterial property and minimum inhibitory concentration (MIc) of gall extract of Quercus infectoria against Enterococcus faecalis...

Nano particles have received increased attention regarding their potential utility in biomedicine. In this study, we have investigated the antibacterial activity of ZnO nano particles with various particle sizes. ZnO nano particles were synthesized by conventional precipitation method using zinc sulphate and sodium hydroxide as precursors followed by the calcinations of precipitates at 350 °C f...