نتایج جستجو برای: anticancer properties
تعداد نتایج: 900251 فیلتر نتایج به سال:
Objective(s):Berberine, a naturally occurring isoquinoline alkaloid, has shown antitumor properties in some in vitro systems. But the effect of berberine on breast cancer has not yet been completely studied. In this study, we evaluated anticancer properties of berberine in comparison to doxorubicin. Materials and Methods: The antiproliferative effects of berberine and doxorubicin alone and in ...
Several reports have shown antimicrobial and anticancer activities of mucous glycoproteins extracted from the giant African snail Achatina fulica. Anticancer properties of the snail mucous peptides remain incompletely revealed. The aim of this study was to predict anticancer peptides from A. fulica mucus. Two of HPLC-separated mucous fractions (F2 and F5) showed in vitro cytotoxicity against th...
In this study, a variety of original ligands related to Combretastatin A-4 and isoCombretastatin A-4, able inhibit the tubulin polymerization into microtubules, was designed, synthesized, evaluated. Our lead compound 15d having quinazoline as A-ring 2-substituted indole B-ring separated by N-methyl linker displayed remarkable sub-nanomolar level cytotoxicity (IC50 < 1 nM) against 9 human cancer...
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