1 Metabolism Section, Medical Service, Department of Veterans Affairs Medical Center, San Francisco, CA 94121; and 2 Department of Medicine, University of California, San Francisco, CA 94143; and 3 Dermatology Service, Department of Veterans Affairs Medical Center, San Francisco, CA 94121; and 4 Department of Pharmaceutical Chemistry and Mass Spectrometry Facility, University of California, San...

The increasing rate of fungal infections causes global problems not only in human healthcare but agriculture as well. To combat pathogens limited numbers antifungal agents are available therefore alternative drugs needed. Antimicrobial peptides potent candidates because their broad activity spectrum and diverse mode actions. model legume Medicago truncatula produces >700 nodule specific cyst...

This study explored the antifungal potential of perillyl alcohol (PA), a natural monoterpene alcohol, against most prevalent human fungal pathogen C. albicans, its clinical isolates and four non-albicans species of Candida. To resolve the potential mechanisms, we used whole genome transcriptome analyses of PA treated Candida cells to examine the affected cellular circuitry of this pathogen. The...

Bioactive potential of apigenin derivative apigenin-7-O-glucoside related to its antifungal activity on Candida spp. and cytotoxic effect on colon cancer cells was studied and compared with bioactive potential of apigenin. Antifungal activity was tested on 14 different isolates of Candida spp. using membrane permeability assay, measuring inhibition of reactive oxidative species and inhibition o...

Laboratoire d’Analyse, Traitement et Valorisation des Polluants de l’Environnement et des Produits, Département de Microbiologie, Faculté de Pharmacie, Monastir, Tunisie. Laboratoire de Traitement des Eaux Usées, Centre de Recherches et des Technologies des Eaux (CERTE), Technopole de Borj-Cédria, BP 273Soliman 8020, Tunisie. Laboratoire d’adaptation des plantes aux stress abiotiques, Centre de...

Abstract Pseudomonas azotoformans known for the benefit on agriculture area as soil fertility enhancer. UICC B-91 was successfully isolated from tissues of N. altissima which traditionally treating infectious diseases. Therefore, endophytic P. might contain antimicrobial compound. This research aims exploring activities several extracts against pathogenic microbes. Isolates were extracted with ...

Carvacrol and eugenol, the main (phenolic) components of essential oils of some aromatic plants, were evaluated for their therapeutic efficacy in the treatment of experimental oral candidiasis induced by Candida albicans in immunosuppressed rats. This anticandidal activity was analyzed by microbiological and histopathological techniques, and it was compared with that of nystatin, which was used...