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BACKGROUND For patients unable to receive heparin anticoagulation during haemodialysis, saline flushes to reduce circuit clotting are often the norm. Regional citrate anticoagulation (RCA) although effective is not used by many centres including in Singapore. We wanted to demonstrate the superiority and safety of a simple regional citrate anticoagulation regime, compared to saline flushes, for ...

results based on the findings, most of the participants (64.5%) were aged 30 - 39 years old. 84% of the cases were female and 97.3% had a bachelor’s degree. the average perceived knowledge of nurses was 2.43 ± 1.01. the nurses had the highest familiarity with triage and lowest knowledge in epidemiology and decision-making. conclusions lack knowledge of nurses regarding response to disaster situ...

Piper chaba Hunter, a flowering vine of Piperaceae family, has been using for long time in south Asian country for culinary meat preparation. As stem and root of this plant has been using traditionally in fat rich meat preparation, the antioxidant and anticoagulation potential of this herb is a great interest of study and it was evaluated using cold and boiled water extract of dried and grinded...

BACKGROUND Emergency department (ED) clinicians are not typically involved in the long-term management of patients' anticoagulation therapy, but they are responsible for decision making for emergency conditions requiring anticoagulation, such as acute venous thromboembolism (VTE). In addition, emergency physicians are often faced with patients who present first to the ED with conditions that ma...

BACKGROUND the efficacy of warfarin for prevention of stroke in patients with atrial fibrillation (AF) is well established, but many people with AF who would benefit from warfarin are not receiving it. This systematic review aims to determine physicians' attitudes to the prescription of warfarin for AF, and identify reasons for its underuse. METHODS an electronic search of MEDLINE (1950-prese...

The management of patients who require temporary interruption of warfarin therapy because of elective surgery or another invasive procedures is clinically important because of the increasing prevalence of patients who are receiving warfarin and the availability of low-molecular-weight heparins, which facilitate out-of-hospital perioperative anticoagulation. The two main issues that need to be c...

BI's baseline annual risk of stroke was 12.5% by CHADS2 score; her 5-year stroke risk by the Framingham tool was 59%. Risk factors for bleeding included diabetes, aspirin use and ibuprofen use, and a moderate fall risk by physical therapy assessment due to her osteoarthritis and deconditioned state. Given her fall risk, she and her family decided against anticoagulation with warfarin. She was d...

• This paper reviews and develops methods for implementing in practice recent ideas in the field of optimal dynamic treatment allocation. Given longitudinal sequences of observational data on health status and treatment selection for a cohort of patients, the aim is to determine a regime, or decision rule, which can be used to select treatment in order to optimise some final response or outcome...