Background: Recurrent pregnancy loss (RPL) is an emotionally painful occurrence for couples and presents Obstetricians with a difficult clinical problem. Because primary etiology cannot be determined in roughly half of the instances, it irritating both patients obstetricians. The present study aimed to determine association antithrombin III gene (SERPINC1) mutation unexplained RPL.Methods: This...

Adults with Asperger Syndrome (AS) can recognise simple emotions and pass basic theory of mind tasks, but have difficulties recognising more complex emotions and mental states. This study describes a new battery of tasks, testing recognition of 20 complex emotions and mental states from faces and voices. The battery was given to males and females with AS and matched controls. Results showed the...

The Sudbury Neutrino Observatory (SNO) has recently completed an analysis of data from the salt phase of the experiment, in which NaCl was added to the heavy-water neutrino target to enhance sensitivity to solar neutrinos. Results from the 391-day salt data set are summarized, including the measured solar neutrino fluxes, the electron energy spectrum from charged current interactions, and the d...

Herein, we report optically pure modified acyclic nucleosides as ideal probes for aptamer modification. These new monomers offer unique advantages in exploring the role played in thrombin inhibition by a single residue modification at key positions of the TBA structure.

a The Sudbury Neutrino Observatory (SNO) has unique capabilities as a supernova detector. In the event of a galactic supernova there are opportunities, with the data that SNO would collect, to constrain certain intrinsic neutrino properties significantly, to test details of the various models of supernova dynamics, and to provide prompt notification to the astronomical community through the Sup...

We investigate the status of the neutrino decay solution to the solar neutrino problem in the context of the recent results from Sudbury Neutrino Observatory (SNO). We present the results of global χ2-analysis for both two and three generation cases with one of the mass states being allowed to decay and include the effect of both decay and mixing. We find that the Large Mixing Angle (LMA) regio...

INTRODUCTION The etiology of preeclampsia is not fully established. A few studies have shown a relationship between natural coagulation inhibitors and preeclampsia. OBJECTIVES The purpose of this study was to investigate the status of natural coagulation inhibitors and active protein C resistance (APC-R) in preeclampsia. PATIENTS AND METHODS We studied 70 women with preeclampsia recruited c...

Previous studies showed that homocysteine, a thrombo-atherogenic and atherogenic agent, inhibits an endothelial thrombomodulin-protein C anticoagulant pathway. We examined whether homocysteine might affect another endothelial anticoagulant mechanism; i.e., heparin-like glycosaminoglycan-antithrombin III interactions. Incubations of porcine aortic endothelial cell cultures with homocysteine redu...

As the pivotal phase III randomized controlled clinical trial on antithrombin concentrate in patients with severe sepsis did not show a beneficial effect of antithrombin treatment on 28-day mortality, the interest in the potential use of this treatment modality in sepsis has diminished. However, recent data on the effect of antithrombin administration on coagulation in combination with recent a...