objective(s) the sst-i polymorphic site on the 3' untranslated region of the apo ciii gene, has been previously reported to be associated with hypertriglyceridemia. the aim of the present study was to explore the association between sst-i polymorphism with plasma lipid and lipoprotein levels in hyperlipidemic (hlp) patients from semnan province, iran. materials and methods genomic dna was ...

sumac (rhus coriaria l.) is used as an herbal remedy in traditional medicine. the aim of this study was to determine the effects of sumac (rhus coriaria l.) on serum glycemic status, apolipoprotein (apo) b, apoa-i and total antioxidant capacity (tac) in type 2 diabetic patients. this double blind randomized controlled clinical trial was conducted on 41 type 2 diabetic volunteers randomly assign...

It has long been established that the Trypanosoma brucei TbAT1/P2 aminopurine transporter is involved in the uptake of diamidine and arsenical drugs including pentamidine, diminazene aceturate and melarsoprol. Accordingly, it was proposed that the closest Trypanosoma congolense paralogue, TcoAT1, might perform the same function in this parasite, and an apparent correlation between a Single Nucl...

b a ckground:  to compare the oxidative stress (os) factors in obese and non- obese subjects with type 2 diabetes (t2d) and to evaluate the interaction between the apolipoprotein a-ii (apo a-ii) - 265t > c polymorphism and body mass index (bmi) on os factors. m ethods : in this comparative cross-sectional study, 21 diabetes centers in tehran, iran were studied. 180 patients with t2d were divide...

A turbidimetric method is described for the determination of apolipoproteins A-I, A-II and B on microtitre plates. Regression analysis of the resulting values showed a good correlation to apolipoprotein values determined turbidimetrically on Cobas Bio (apolipoprotein A-I, A-II), and those determined by means of radial immuno diffusion (RID) (apolipoprotein A-I: r = 0.93, y = 1.02 x - 5.0, n = 6...

Apolipoprotein B, the major protein of low-density lipoprotein, and apolipoprotein A-I, the major protein of high-density lipoprotein, can serve as important predictors of atherosclerotic cardiovascular disease. However, these apolipoprotein measurements have not realized their full potential because of inadequate standardization. Purified apolipoprotein A-I of known absolute mass, in lyophiliz...

Lipoprotein(a) contains one copy each of apolipoprotein B-100 and apolipoprotein(a). It has been hypothesized that a disulfide bond might exist between Cys4057 of apolipoprotein(a) and Cys3734 in apolipoprotein B-100. To investigate the role of Cys4057 for lipoprotein(a) assembly, wild-type and in vitro mutagenized apolipoprotein(a) cDNA plasmids were expressed in the human hepatocarcinoma line...

Apolipoprotein M (Apo-M) is a human novel protein of apolipoprotein classes and highly expressed in liver and kidney tissues. ApoM is mainly associated with high-density lipoprotein (HDL), and act as a chaperone for sphingosine-1-phosphate (S1P), promotes mobilization of cellular cholesterol, formation of larger-size of pre β-HDL, and a new biomarker in sepsis. The level of apoM in plasma/s...

Results of genome-wide linkage analyses to identify chromosomal regions that influence interindividual variation in plasma lipid and apolipoprotein levels in the Rochester, Minn, population are reported. Analyses were conducted for total cholesterol (total-C), triglycerides (TGs), high density lipoprotein cholesterol (HDL-C), apolipoprotein A-I, apolipoprotein A-II, apolipoprotein B, apolipopro...