نتایج جستجو برای: apolipoproteins e
تعداد نتایج: 1023956 فیلتر نتایج به سال:
Apolipoprotein (apo) E is a 34-kDa glycoprotein associated with plasma lipoproteins. In contrast to other apolipoproteins, apoE is expressed ubiquitously in all tissues and appears to have a wide variety of functions in addition to lipid transport. Although the lipid transport properties of apoE are well characterized, the appreciation apoE functions other than lipid transport is still in an in...
Kevin D. O'Brien, Katherine L. Olin, Charles E. Alpers, Winnie Chiu, Marina Ferguson, Kelly Atherosclerotic Plaques : Colocalization of Biglycan With Apolipoproteins Comparison of Apolipoprotein and Proteoglycan Deposits in Human Coronary Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 1998 American Heart Association, Inc. All rights reserved. is published by the American Heart Associ...
Background and Aim: Lipoprotein disorders are an integral component of type-2 diabetes mellitus (T2DM). Therefore, early diagnosis and treatment of lipid disorders can be beneficial in prevention and treatment of many complications associated with T2DM.The aim of this study wasto determine the effect of docosahexaenoic acid (DHA) supplementation on the serum levels of apolipoproteins (Apos) A1,...
The loss of ABCA1 function leads to Tangier dyslipidemia in humans and to a Tangier-like phenotype in mice, by impairing the transformation of nascent apolipoproteins into mature HDL particles. Mechanistically this ensues from the inability of cells to release membrane lipids and cholesterol. Whereas the ability of ABCA1 to promote phospholipid effluxes, surface binding of apolipoproteins and o...
CONTEXT Associations of major lipids and apolipoproteins with the risk of vascular disease have not been reliably quantified. OBJECTIVE To assess major lipids and apolipoproteins in vascular risk. DESIGN, SETTING, AND PARTICIPANTS Individual records were supplied on 302,430 people without initial vascular disease from 68 long-term prospective studies, mostly in Europe and North America. Dur...
The two major apolipoproteins associated with human and chimpanzee (Pan troglodytes) high density lipoproteins (HDL) are apoA-I and dimeric apoA-II. Although humans are closely related to great apes, apolipoprotein data do not exist for bonobos (Pan paniscus), western lowland gorillas (Gorilla gorilla gorilla) and the Sumatran orangutans (Pongo abelii). In the absence of any data, other great a...
our synthetic ape C-il (46-58) gave a negative response when tested with purified native apolipoprotein C-fl. Double iminunodiffusion (Ouchterlony technique) of antibodies against our synthetic ape E (141-155) gave a positive immunoprecipitation line with Purified apolipoprotein E, which showed a partial identity with those obtained with polyclonal antibodies raised against the native protein. ...
The hyperlipidemia associated with aging was characterized in the rat by comparing the plasma lipid, lipoprotein, and apolipoprotein profiles of adult (12 weeks old) and old (96 weeks old) male rats. Compared with those of the adult rats, the VLDL concentrations of the old rats were reduced, but IDL, LDL, and HDL concentrations were elevated. Despite a reduced VLDL concentration, concentrations...
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