نتایج جستجو برای: apri
تعداد نتایج: 542 فیلتر نتایج به سال:
BACKGROUND Liver diseases progress faster in human immunodeficiency virus (HIV)-hepatitis C virus (HCV)-coinfected persons than HIV-monoinfected persons. The aim of this study was to compare rates of liver fibrosis progression (measured by the aspartate-to-platelet ratio index [APRI]) among HIV-HCV-coinfected users of modern protease inhibitor (PI)- and nonnucleoside reverse transcriptase inhib...
BACKGROUND/AIMS The aims of this study were to evaluate the effect of antiviral therapy on serum total cholesterol (TC) levels and to investigate the factors related to serum TC changes in chronic hepatitis C (CHC) patients. METHODS A total of 94 CHC patients, the majority of whom were infected with genotype 1 or 2 and were receiving antiviral therapy, were consecutively enrolled. TC levels b...
BACKGROUND Patients with HIV mono-infection may develop chronic liver disease due to a number of factors including hepatic steatosis. We estimated the prevalence and predictors of hepatic steatosis and fibrosis in a cohort of HIV-mono-infected patients with persistently deranged liver function tests. METHODS Of 2398 consecutive patients at one UK clinical center, 156 (6.5%) had persistently a...
The aim of the present study was to evaluate the prognostic significance of serum markers that reflect tumor progression, liver function, or liver fibrosis in patients with hepatocellular carcinoma (HCC), focusing on how their impact changes over time after diagnosis. Alpha-fetoprotein (AFP), des-gamma-carboxy prothrombin (DCP), albumin-bilirubin (ALBI) score, aspartate aminotransferase to plat...
BACKGROUND Ukraine's injecting drug use-driven HIV epidemic is among the most severe in Europe with high burden of HCV co-infection. HIV/HCV co-infected individuals are at elevated risk of HCV-related morbidity, but little is known about burden of liver disease and associated factors in the HIV-positive population in Ukraine, particularly among women. METHODS Characteristics of 2050 HIV-posit...
Aspartate aminotransferase-to-platelet ratio (APRI), aspartate aminotransferase-to-alanine aminotransferase ratio (AAR), FIB-4, FI, King, Lok, Forns, and FibroIndex scores may be simple and convenient noninvasive diagnostic tests, because they are based on the regular laboratory tests and demographic data. This study aimed to systematically evaluate their diagnostic accuracy for the prediction ...
Chronic liver disease of various etiologies is the major causes mortality and morbidity globally. Liver biopsy most accurate oldest method to determine chronic progression for histology. Shear wave elastography (SWE) a new non-invasive technique that applies localized mechanical compression soft tissue with focused ultrasonography obtains tension images showing response. Aspartate aminotransfer...
BACKGROUND Liver biopsy (LB) is still considered to be the gold standard for assessment of liver fibrosis. OBJECTIVES To evaluate the effectiveness of various non-invasive methods for predicting liver fibrosis, including transient elastography (TE), APRI score, Lok score, Forns score, FIB-4 score, Fibrosis Index, King score, and Bonacini score, in comparison with the effectiveness of LB and t...
BACKGROUND AND AIMS Non-alcoholic fatty liver disease (NAFLD) is a common, morbid disease with profound implications for the overall health of the patient. We set out to determine the clinical predictors of advanced histology in the referral population. METHODS We performed a retrospective review of all biopsy-proven NAFLD patients, including 358 unique patients first seen between 1996 and 20...
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