BACKGROUND Many adults with autism spectrum disorder (ASD) remain undiagnosed. Specialist assessment clinics enable the detection of these cases, but such services are often overstretched. It has been proposed that unnecessary referrals to these services could be reduced by prioritizing individuals who score highly on the Autism-Spectrum Quotient (AQ), a self-report questionnaire measure of aut...

OBJECTIVES Recent studies have shown that women with autism spectrum disorder have higher rates of menstrual problems, including irregular menstrual cycles, unusually painful periods (dysmenorrhea), and excessive menstrual bleeding. In this study, we investigated the autistic traits in female university students with primary dysmenorrhea (PD). METHODS Seventy females with PD and 70 females wi...

Amyloid aggregation is linked to a number of neurodegenerative syndromes, the most prevalent one being Alzheimer's disease. In this pathology, the beta-amyloid peptides (Abeta) aggregate into oligomers, protofibrils, and fibrils and eventually into plaques, which constitute the characteristic hallmark of Alzheimer's disease. Several low-molecular-weight compounds able to impair the Abeta aggreg...

PURPOSE To evaluate the time course of drug concentrations achieved in aqueous (AQ), vitreous (V), and serum (S) compartments after oral administration of linezolid and levofloxacin. DESIGN Randomized, clinical trial. METHODS SETTINGS Clinical practice. PATIENT POPULATION Sixteen patients (16 eyes) undergoing vitrectomy who had not had a prior pars plana vitrectomy in the study eye wer...

Anthraquinone spermine [N1-(anthraquinone-2-carbonyl)spermine; AQ343], anthraquinone homospermine [N1-(anthraquinone-2-carbonyl; AQ444], anthracene spermine [N1-(9-anthracenylmethyl)spermine; Ant343], and anthracene homospermine [N1-(9-anthracenylmethyl)homospermine; Ant444] were found to be potent antagonists of recombinant N-methyl-D-aspartate (NMDA) receptors (NRs). The effects of both anthr...

In the current study, the child AQ was administered in Japan, to examine whether the UK results for reliability and validity generalize to a different culture. Assessment groups were: Group 1: n = 81 children with Asperger Syndrome (AS) or high-functioning autism (HFA); Group 2: n = 22 children diagnosed PDD-NOS with average IQ; and Group 3: n = 372 randomly selected controls from primary and s...

Let f ∈ L2(S2) be an arbitrary fixed function on the unit sphere S2, and D ⊂R3 be an arbitrary fixed bounded domain. Let k > 0 and α ∈ S2 be fixed. It is proved that there exists a potential q ∈ L2(D) such that the corresponding scattering amplitude A(α′) = Aq(α′) = Aq(α′, α, k) approximates f (α′) with arbitrary high accuracy: ‖f (α′)−Aq(α′)L2(S2)‖ ε where ε > 0 is an arbitrarily small fixed n...

This is a review article covering literature reported on consolidation of ceramic components out of aq.-based Al2O3, MgAl2O4 spinel, β-Si4Al2O2N6, β-SiAlON-SiO2 composite, and zirconia toughened alumina (ZTA) slurries following hydrolysis induced aq. gelcasting (henceforth referred to as GCHAS) route. GCHAS is a combination of aq. gelcasting (GC) and hydrolysis assisted solidification (HAS) rou...

PURPOSE Aggression in people with epilepsy (PWE) is not well understood. We investigated interictal aggression in PWE and clarified predictors and the interrelationships among them. METHOD This was a case-control study. Eligible subjects who consecutively visited the epilepsy clinic completed several questionnaires including the Aggression Questionnaire (AQ), the Revised Stigma Scale (RSS), t...