Developmental stage-, subset-, and lineage-specific CD8 enhancers have been identified recently by transgenic reporter analyses. Enhancer E8(II) (CIV-4,5) is active in both immature double-positive thymocytes (DP) and mature CD8 single-positive (SP) thymocytes and T cells, whereas E8(I) (CIII-1,2) directs expression only in mature cells. In mice lacking either E8(I) (CIII-1,2) or E8(II) (CIV-4,...

Analytic number theorists usually seek to show that sequences which appear naturally in arithmetic are “well-distributed” in some appropriate sense. In various discrepancy problems, combinatorics researchers have analyzed limitations to equi-distribution, as have Fourier analysts when working with the “uncertainty principle”. In this article we find that these ideas have a natural setting in th...

The linear discrepancy of a poset P is the least k such that there is a linear extension L of P such that if x and y are incomparable, then |hL(x)− hL(y)| ≤ k. Whereas the weak discrepancy is the least k such that there is a weak extension W of P such that if x and y are incomparable, then |hW (x)− hW (y)| ≤ k. This paper resolves a question of Tanenbaum, Trenk, and Fishburn on characterizing w...

Purpose The density peak clustering algorithm (DP) is proposed to identify cluster centers by two parameters, i.e. ρ value (local density) and δ (the distance between a point another with higher value). According the center-identifying principle of DP, potential should have than other points. However, this may limit DP from identifying some categories multi-centers or in lower-density regions. ...

In his space-time approach to quantum electrodynamics, Feynman advocated: “It is obviously simpler to disregard the exclusion principle completely in the intermediate states” [1]. He examined processes involving several particles and observed that all virtual processes that violate Pauli’s exclusion principle (formally) cancel out. It is understood that all virtual processes of the same orders ...

the a priori is the basic characteristic ofkant's theory of knowledge. formaliz/ng the a priori, kant appears to distinguish the a priorifrom the postriori and qffirms its purity. he insists that the a priori is prior to the a postriori and stqys independent!jfrom it. the overall objectiue of this paper is, boueier; to present and to support this idea that the a priori, even prior, can be ...

When the position of each input vector in the training set is not fixed beforehand, a deterministic approach can be adopted to face with the general problem of learning. In particular, the consistency of the Empirical Risk Minimization (ERM) principle can be established, when the points in the input space are generated through a purely deterministic algorithm (deterministic learning). When the ...

We show that the complex modified KdV (cmKdV) equation and generalized nonlinear Schrödinger (GNLS) equation belong to the Ablowitz, Kaup, Newell and Segur or so-called AKNS hierarchy. Both equations do not follow from the action principle and are nonintegrable. By introducing some auxiliary fields we obtain the variational principle for them and study their canonical structures. We make use of...

Abstract With the advent of big data era and advancement social network analysis, public is increasingly concerned about privacy protection in today’s complex networks. For past few years, rapid development differential (DP) technology, as a method with reliable theoretical basis, can effectively solve key problem how to “disassociate” personal information This paper focuses on multi-mode heter...

[1] The consistency of precipitation variability estimated from the multiple satellite-based observing systems is assessed. There is generally good agreement between TRMM TMI, SSM/I, GPCP and AMSRE data sets for the inter-annual variability of precipitation since 1997 but the HOAPS data set appears to overestimate the magnitude of variability. Over the tropical ocean the TRMM 3B42 data set prod...