New Schiff bases derivatives from lauric acid were synthesized through the condensation of dodecane methyl ester with hydrazine to give corresponding hydrazide, which react aromatic aldehyde afford dodecanehydrazide-hydrazones and carbon disulfide 1,3,4-oxadiazole-2-thion. The chemical structures confirmed by numerous characterization methods; including Infrared, Ultraviolet-Visible, 1H 13C Nuc...

The Baeyer–Villiger oxidation (BVO) of ketone and aldehyde can produce ester formate, which both have wide applications in many areas. In this work, a series Sn-containing silicates were prepared through the sol-gel process by using structure-directing crystallizing agents post-synthetic coordinated modification binaphthol. Characterizations revealed that loading (L)-sodium lactate as agent dec...

The title compound, [Ge(CH3)3(C7H5O2)], was obtained as a by-product in the synthesis of the corresponding aldehyde. Two slightly different mol-ecules are present in the asymmetric unit. In both mol-ecules, the geometry of the aromatic ring plane is distorted by varying intensities. Additionally, the Ge atoms deviate from the mean aromatic ring planes. Whereas the distance of the Ge atom to the...

A regioselective vinylation of aromatic and aliphatic aldehydes promoted by the merging photoredox nickel catalysis is here reported. comprehensive investigation on reaction conditions allowed disclosure a valid reproducible protocol based nickel-mediated reductive coupling approach under visible light irradiation. The employment 3CzClIPN (2,4,6-tris(carbazol-9-yl)-5-chloro-isophthalonitrile) a...

A mild method for the cross-coupling of arylboronic acids with CF3I via the merger of photoredox (to generate CF3 radical) and Cu catalysis (to generate reactive Cu−aryl species) was developed by Professor Sanford and her co-worker of University of Michigan (J. Am. Chem. Soc. 2012, 134, 9034− 9037). Potassium carbonate was found a base of choice for the promotion of transmetalation in DMF solve...

Aldehyde dehydrogenase 7A1 (ALDH7A1) is part of lysine catabolism and catalyzes the NAD(+)-dependent oxidation of α-aminoadipate semialdehyde to α-aminoadipate. Herein, we describe a structural study of human ALDH7A1 focused on substrate recognition. Five crystal structures and small-angle X-ray scattering data are reported, including the first crystal structure of any ALDH7 family member compl...

In this paper, we describe the efficient and selective synthesis of aryldipyrromethanes in aqueous medium by acid-catalyzed (HCl) condensations of aromatic aldehydes with 3 equivalents of pyrrole at room temperature. The precipitated aryldipyrromethanes can be isolated directly from the reaction mixture in an essentially pure state by simple filtration. Time control seems to be essential to avo...

Abstract In this study, we evaluated the performance of nano-?-Fe 2 O 3 –SO H catalyst in Biginelli reaction and synthesized 3,4-dihydropyrimidine-2-(1 )-ones. This was carried out under solvent-free ultrasonic irradiation conditions belonged to one-pot multicomponent reactions (MCRs) with an adopted aromatic aldehyde, ethyl acetoacetate, urea as starting materials for beginning reaction. The w...

Irradiation of dithiane-aldehyde/ketone adducts in the presence of benzophenone leads to C-C bond cleavage regenerating the carbonyl compounds. It is established that the mechanism of this reaction involves photochemically induced single electron transfer from the dithiane moiety to the excited molecule of ET-photosensitizer, accompanied by mesolytic C-C cleavage in the generated cation-radical...

2-Chloro-3-methylquinoxaline was selected as a nucleus around which various molecular transformations were performed to obtain new compounds expected to possess optimized antimicrobial activity. As very little work regarding attachment of ether linkages replacing chlorine at C-2 has been reported, it was thought worthwhile to synthesize various quinoxaline derivatives by replacing the C₂ chlori...