Cerebral ischemia was produced by a combination of vascular occlusion and mild systemic hypotension in 2 groups of rabbits. Arterial blood pressure, arterial pH, arterial blood gases, blood glucose and PCV were monitored and recorded before, during and for 3 hours after reperfusion. Return of EEG activity, vasomotor control, spontaneous ventilation and corneal reflex were also recorded. At 4, 8...

BACKGROUND Fear of infection limits the willingness of laymen to do cardiopulmonary resuscitation (CPR). This study assessed the time course of change in arterial blood gases during resuscitation with only chest compression (no ventilation) in an effort to identify the time for which ventilation could be deferred. METHODS AND RESULTS Aortic pressures and arterial blood gases were monitored in...

STUDY OBJECTIVE To evaluate the short-term physiologic effects of two settings of nasal pressure-support ventilation (NPSV) in stable COPD patients with chronic hypercapnia. DESIGN Randomized controlled physiologic study. SETTING Lung function units and outpatient clinic of two affiliated pulmonary rehabilitation centers. PATIENTS Twenty-three patients receiving domiciliary nocturnal NPSV...

We studied the airway gas exchange properties of five inert gases with different blood solubilities in the lungs of anesthetized sheep. Animals were ventilated through a bifurcated endobronchial tube to allow independent ventilation and collection of exhaled gases from each lung. An aortic pouch at the origin of the bronchial artery was created to control perfusion and enable infusion of a solu...

Until the late 1960's there was a remarkable lack of information on the consequences of asthma on arterial oxygenation [1, 2). Since then, it has been known that arterial blood gas abnormalities can range from overt hypoxaemia, usually associated with hypocapnia and respiratory alkalosis, as shown in acute severe asthma, to mild increases in the alveolar-arterial 0 2 tension difference (AaPo,) ...

SUMMARY Arterial and mixed venous oxygen tensions were measured in 24 patients following acute myocardial infarction while they were breathing air and 100% oxygen. Total venous admixture and the right-to-left shunt during 100% oxygen breathing were calculated. These data were related to the pulmonary arterial diastolic pressure, the cardiac index, and the central blood volume. Patients with myo...

BACKGROUND Tracheostomy decreases airway resistance and work of breathing. No comprehensive data are available on respiratory mechanics after tracheostomy decannulation. We evaluated respiratory mechanics after decannulation. METHODS Twenty-five patients with tracheostomy were included. Measurement of arterial blood gases, air-flow, and esophageal pressure during spontaneous breathing were ev...