BACKGROUND Kinematically aligned total knee arthroplasty strives to correct the arthritic deformity by restoring the native tibial joint line. However, the precision of such surgical correction needs to be quantified in order to reduce recuts of the resection and to design assisting instrumentation. This study describes a method for novel three-dimensional analysis of tibial resection parameter...

  Multiplanar or global laxity in arthritic knee is rare , most of this patients have neuromuscular disorder (post poliomyelitis , spinal dystrophy) or history of knee trauma. Ligament insufficiency and severe bone loss is significant in this patient. The estimated prevalence for the concurrence of charcot marie-tooth (CMT) with myasthenia gravis (MG) suggests an extremely rare event. We have p...

multiplanar or global laxity in arthritic knee is rare , most of this patients have neuromuscular disorder (post poliomyelitis , spinal dystrophy) or history of knee trauma. ligament insufficiency and severe bone loss is significant in this patient. the estimated prevalence for the concurrence of charcot marie-tooth (cmt) with myasthenia gravis (mg) suggests an extremely rare event. we have pre...

Adjuvant induced arthritis is a chronic crippling, skeleton-muscular disorder having nearest approximation to human rheumatoid arthritis for which there is currently no medicine available effecting a permanent cure. Even modern drugs used for the amelioration of the symptoms, offer only temporary relief and also produce severe side effects. In the indigenous system of medicine, wood of Premna s...

Using a preclinical in vivo model of arthritis and the gold standard disease-modifying anti-rheumatic drug, methotrexate, pH-responsive phosphorylcholine polymersomes, elicit both anti-inflammatory anti-arthritic therapeutic efficacy, while drastically minimizing off-target toxicity. First, selective accumulation polymersomes within synovium inflamed joints. Second, targeting ability toward act...

Pharmacognosy Research,2023,15,3,478-483.DOI:10.5530/pres.15.3.049Published:June 2023Type:Original Article Authors:Bapan Banik, and Malay Kumar Das Author(s) affiliations:Bapan Das* Department of Pharmaceutical Sciences, Drug Delivery Research Laboratory, Dibrugarh University, Dibrugarh, Assam, INDIA. Abstract:Background: The different parts Alstonia scholaris (AS) viz. leaf, bark root, latex a...

The capacity of exudative neutrophils to phagocytose and digest fibrin, an important constituent of inflammatory exudates, was investigated in various types of arthritis. In addition, the catheptic enzyme content of inflammatory cells was established directly with the aid of fluorescent anticathepsin. The intracellular organization of cathepsin varied considerably among the patients. The distri...