P soriatic arthropathy is a common inflammatory arthritis that characteristically occurs in individuals with psoriasis [1]. PsA was classified as a distinct entity for the first time in 1964 [2], but the antiquity of this disease can be dated back tens of centuries [3]. The many faces of PsA have historically complicated the timely diagnosis on the one hand, while its aggressive and destructive...

Accepted for publication 17 November 1994 Clinical history An 84 year old Chinese woman presented with a one year history of increasingly severe right shoulder pain, associated with joint stiffness. There were no symptoms related to the rest of the upper limb or neck. On examination, a soft tissue mass was palpable over the anterior aspect of the right shoulder. The mass measured about 6 cm in ...

Primary biliary cirrhosis (PBC) is a chronic progressive cholestatic liver disease with fibrosis leading to cirrhosis [1–3] and liver failure [4,5]. PBC is often thought of as an organ-specific autoimmune disease, which mainly targets the liver; however, other tissue also can be a site for autoimmune involvement of PBC. Jaccoud’s arthropathy (JA) was a nonerosive deforming arthropathy initially...

Arthropathy – or joint disease is the most common post-cranial pathological change found in skeletal remains, both today and past. Responsible for a great amount of pain discomfort modern populations, arthropathy continues to be highly researched current clinical pale­opathological studies. Despite its frequency an archaeological context, differentiation between various types can prove challeng...

Arthropathy is a serious and common problem in patients with hemophilia impairing the patient’s quality of life seriously. The most commonly affected joints hemophilic arthropathy are knees, ankles elbows. Even single bleeding could cause devastating effects to synovium, cartilage also subchondral bones. Ultrasound magnetic resonance imaging have been advocated for studying damage. Prophylaxis ...

OBJECTIVES The intra-articular pressure (IAP) rises significantly after isometric quadriceps contraction in patients with rheumatoid synovitis, a process that may temporarily impede synovial blood flow and cause oxidative injury. In acute traumatic knee effusions (ATE) pressure rises are trivial. This study compared the IAP profiles of patients with ATE with three different populations--an acut...

In this issue of Blood, Acharya and colleagues provide evidence for the role of angiogenesis in the pathophysiology of hemophilic joint disease. Is this the linchpin that unravels this important clinical condition or merely a cog in a not so stepwise process?

To investigate the pathogenesis of human T cell lymphotropic virus type I (HTLV-I)-associated chronic inflammatory arthropathy (HAAP), we sought to detect proviral DNA in the articular lesions. For the detection of proviral DNA, we used the polymerase chain reaction (PCR). Proviral DNA was detected not only in the peripheral blood mononuclear cells (PBMCs) and synovial fluid cells (SFCs), but a...

Psoriatic arthropathy (PsA) is an inflammatory arthropathy associated with skin or nail psoriasis with heterogeneous clinical manifestations. A pragmatic therapeutic approach to PsA is to stratify the disease manifestations according to their response to synthetic and biological agents. It is now reasonably well established that peripheral arthritis is amenable to treatment with synthetic disea...

Syringomyelia is characterized by slow progression; the joints involved most frequently are the shoulders and elbows. Neuropathic arthropathy of the hand is quite rare. Herewith, we present a case of neuropathic arthropathy (NA) of the joints in the upper limb secondary to Syringomyelia. Atypical features of the case included NA of the shoulder, elbow and metacarpophalengeal joint in the same u...