George Katritsis, BSc, MB ChB, Ashish S. Shah, MD, Cynthia A. James, PhD, Brittney Murray, MS, Crystal Tichnell, MGC, Daniel P. Judge, MD, Hugh Calkins, MD, FHRS, Ryan J. Tedford, MD From the The ARVD/C Program, The Johns Hopkins Hospital, Baltimore, Maryland, The John Radcliffe Hospital, Nuffield Department of Medicine, Oxford University Hospital, Oxford, United Kingdom, and Department of Card...

Background cMRI is frequently used to assess right ventricular (RV) morphology and function in patients with suspected ARVD and is the gold standard for fatty metaplasia amongst all non-invasive imaging tests. However, the incidence and severity of RV fatty infiltration by cMRI is not well defined. Here, stratified by age, we investigate the prevalence and severity of RV fat infiltration in a l...

Historically, left ventricular cardiomyopathy and coronary heart disease have been regarded as the main causes of ventricular arrhythmia and sudden cardiac death. However, within last two decades, arrhythmias originating from the right ventricle have begun to attract the attention of the scientific world for a number of reasons. Ventricular arrhythmias originating from the right ventricle usual...

Background Right ventricular (RV) regional wall characteristics are important in CMR evaluation for arrhythmogenic RV dysplasia (ARVD). While some features are well defined, others are of uncertain clinical significance, due in part, to the high prevalence of RV wall motion variants found in normal subjects. In this study we performed a retrospective review of RV free wall characteristics in a ...

BACKGROUND Radiofrequency ablation (RFCA) became a treatment of choice in patients with recurrent ventricular tachycardia, ventricular fibrillation, and appropriate interventions of implanted cardioverter-defibrillator (ICD), however, electrical storm (ES) ablation in a pregnant woman has not yet been reported. CASE PRESENTATION We describe a case of a successful rescue ablation of recurrent ...

Atheromatous renovascular disease (ARVD) is a commonly encountered yet challenging disease to manage. Renal artery stenosis (RAS) is usually focal and is of great clinical importance, not only due to the potential blood flow-limiting effects upon the renal circulation (and subsequent intra-renal ischaemia), but also downstream neuro-hormonal and cytokine release resulting in hypertension, renal...

Arrhythmogenic right ventricular dysplasia is an inherited fatal cardiomyopathy causing fat and connective tissue infiltration of right ventricle. In advanced disease, it may also involve left ventricle. Heart failure, arrhythmias and sudden death are main clinical components. Many different genetic mutations can cause this cardiomyopathy. All mutations lead to the formation of the disease are ...

OBJECTIVES Gated radionuclide ventriculography (RNV) may be used for the evaluation of the right ventricular function. However, the accuracy of the method should be clinically validated in patients suffering from diseases with specific pathology of the right ventricle (RV) and with possible left ventricular (LV) interaction. METHODS Three groups of 15 patients each, diagnosed with arrhythmoge...

BACKGROUND Arrhythmogenic right ventricular dysplasia (ARVD), is a genetic disorder of the heart, which mainly involves the right ventricle. It is characterized by hypokinetic areas at the free wall of the right ventricle (RV) or both ventricles, where myocardium is replaced by fibrous or fatty tissue. ARVD is an important cause of ventricular arrhythmias in children and young adults. Although ...