Objective: Sickle cell anemia is a condition resulting from inheritance of two abnormal allele genes controlling β-globin formation. This haemoglobinopathy affects multiple organ system in the body. The hepatobiliary most commonly affected sickle disease. study assessed liver enzymes activities subjects Enugu, Nigeria. Methods: We recruited about hundred age (20-40years) for this study. Fifty (...

1. Alanine Aminotransferase (ALT) Alanine aminotransferase measurements are used in the diagnosis and treatment of certain liver diseases (e.g., viral hepatitis and cirrhosis) and heart diseases. Elevated levels of the transaminases can indicate myocardial infarction, hepatic disease, muscular dystrophy, or organ damage. Serum elevations of ALT activity are rarely observed except in parenchymal...

Clinical Enzymology Enzymes nomenclature, classification, structure and specificity Enzymes, isoenzymes and their relevance in diagnosis Regulation of enzyme levels in serum and plasma Selection of enzyme tests Measurement of isoenzymes and isoforms Some important enzymes in clinical practice Aspartate transaminase (AST) and Alanine transaminase (ALT) Creatine Kinase (CK) Lactate dehydrogenase ...

Submit Manuscript | http://medcraveonline.com Abbreviations: AST: Aspartate Aminotransferase; BALB/c: An Albino, Laboratory-bred Strain of the House Mouse; BW: Body Weight; CAR: Coxsackie and Adenoviruses Receptor; CK: Creatine Kinase; DCM: Dilated Cardiomyopathy; DMEM: Dulbecco’s Modified Eagle Medium; EMEM: Eagle’s Minimum Essential Medium; GMK: Green Monkey Kidney; HW: Heart Weight; LDH: Lac...

Section Editor: Alfredo José Mansur ([email protected]) Associated Editors: Desidério Favarato ([email protected]) Vera Demarchi Aiello ([email protected]) The laboratory assessment on June 2008 showed: total cholesterol 157 mg/dl, HDL-cholesterol 34 mg/dl, LDLcholesterol 107 mg/dl, triglycerides 83 mg/dl, TSH 0.595 mUI/ml, blood glucose 92 mg/dl, aspartate aminotransferase (AST) ...

Markers of infectious-inflammatory process were studied by determining the levels pro-inflammatory cytokines - interleukin (IL) 1 and IL-6 proteins acute phase inflammation C-reactive protein (CRP) fibrinogen in serum children with community-acquired pneumonia. 
 It was found that course pneumonia is accompanied an increase concentrations IL-1 parallel disease severity. The synthesis stimu...

Background: Nonalcoholic fatty liver disease is a common cause of chronic diseases in developed countries. Ultrasound imaging widely used evaluation disease. The alanine transaminase and aspartate are laboratory investigations diagnosing diseases. Methodology: A cross sectional study was conducted at the Rizgary Hawler teaching hospitals from March to 2021 April 2022 on sample one hundred fifty...

BACKGROUND Serum aminotransferase concentrations are reportedly strongly associated with insulin resistance, an established cardiovascular risk factor that is not routinely assessed in clinical practice. We therefore explored the possibility that serum aminotransferase concentrations are as closely related to large artery disease as insulin resistance in rheumatoid arthritis (RA). METHODS Car...

The outbreak of the novel coronavirus SARS-CoV-2 epidemic has rapidly spread and still poses a serious threat to healthcare systems worldwide. In present study, electronic medical records containing clinical indicators related liver injury in 799 COVID-19-confirmed patients admitted hospital Madrid (Spain) were extracted analyzed. Correlation between disease outcome was also evaluated. Serum le...