Different pril and pri2 conditional mutants of Saccharomyces cereuisiae altered, respectively, in the small (p48) and large (p58) subunits of DNA primase, show an enhanced rate of both mitotic intrachromosomal recombination and spontaneous mutation, to an extent which is correlated with the severity of their defects in cell growth and DNA synthesis. These effects might be attributable to the fo...

In 1972 and 1973 the Pioneer 10 and 11 missions were launched. They were the first to explore the outer solar system and achieved stunning breakthroughs in deepspace exploration. But beginning in about 1980 an unmodeled force of ∼ 8× 10−8 cm/s2, directed approximately towards the Sun, appeared in the tracking data. It later was unambiguously verified as being in the data and not an artifact. Th...

It is not uncommon to hear university students complain about boring classes. The negative effects of boredom, which are at times larger than that of anxiety, have resulted in a concerted effort from researchers to identify causes of learners’ boredom and recommend strategies to mitigate this emotion. However, the research has overlooked the possibility that emotions may be transmitted from ins...

In their recent publication, Garcia-Pola et al. (1) (2016) suggested the development of proliferative verrucous leukoplakia (PVL) in oral lichen planus (OLP). It was described as a preliminary study, where this association supposedly occurred. They presented a retrospective analysis with a long-term follow-up, showing an interesting relationship between these lesions. It is important to emphasi...

Using a panel data set of bilateral export flows from 12 EU countries to 20 OECD trading partners over the period 1992-2003, a panel cointegration approach to estimating the gravity model is adopted to test for the significance of European regional integration. A comparison of the results indicates that a positive and significant coefficient estimate of the EU dummy variable is found for both t...

Polarization is the phenomenon that describes the oscillations orientation of the light (or other radiation) waves which are restricted in direction [1]. Light’s vector orientation can be weekly detected by some humans with their naked eyes, but humans need the help of polarizing optics to visulize most invisible polarization effects [2]. Many fish, cephalopods, crustaceans, insects, and other ...

Rudolf Kirchmair, Young-sup Yoon, Cynthia Curry, Marcy Silver, Marianne Kearney, Kengo F. Kusano, Karen L. Allendoerfer, William Munger, Roberto Pola, Marta Bosch-Marce, in Diabetic Neuropathy Sonic Hedgehog Induces Arteriogenesis in Diabetic Vasa Nervorum and Restores Function Print ISSN: 1079-5642. Online ISSN: 1524-4636 Copyright © 2004 American Heart Association, Inc. All rights reserved. G...

Vascular endothelial cells respond to changes in blood fl ow (1). Increased fl ow, for example, causes vasodilation and blood vessel remodeling. Collectively, these responses are critical for both vascular development and the maintenance of adult blood vessels. Moreover, disturbed blood fl ow patterns—at artery branch points, for instance—can activate infl ammatory pathways that may initiate th...

Frank E. Block, Jr., MD Every clinician is well aware of the problems with audible alarms: False alarms, loud alarms, difficulty determining what is alarming, and inability to quiet an alarm all create distractions that impede patient care. These problems are complicated by the different approaches to alarms among devices. Devices designed by various manufacturers may use different alarm sounds...

Introduction Permit me to begin by telling you a little about the history of the book1 on which this talk2 is based. It will help you understand why I am so delighted to be presenting this talk. On the very day thirty-five years ago when my History of Vector Analysis was published, a good friend with the very best intentions helped me put the book in perspective by innocently asking: “Who was V...