Hypertrophic obstructive cardiomyopathy (HOCM), which shows left ventricular outflow pressure gradient (LVPG), is often complicated with mitral regurgitation (MR). We examined a 62-year-old Japanese female with HOCM and MR. Ultrasound echocardiography showed severe MR, asymmetrical septal hypertrophy, systolic anterior movement of the mitral valve anterior leaflet, and left ventricular outflow ...

objective(s):   gold nanoparticles (gnps) command a great deal of attention for biomedical applications nowadays. the data about the degree of toxicity and the accumulation of gold nanoparticles in-vivo is not enough to judge.  materials and methods:  a total of 32 healthy male wistar rats were randomly divided into 4 including: three gnp-treated and one control group. groups 1, 2 and 3 receive...

A 10-year old boy, product of a non-consanguineous parents presented with developmental delay and poorly controlled seizures. On examination he had features suggestive of atypical growth of the body. There were asymmetric overgrowth of the skull, downward slanting of the palpebral fissures with ptosis, an epibulbar dermoid in the right eye (Figure 1) and a bony tumour (hyperostosis) of the exte...

Results Thirty-nine percentof patients repeated the DSH.Theywere atgreater relative riskof suicide thanthe singleepisode DSHgroup (2.24; 95% CI1.77^ 2.84).The relative riskof suicide in the repeated DSHgroup comparedwiththe single-episode DSHgroupwasgreater in females (3.5; 95% CI1.3^2.4) thanmales (1.8; 95% CI 2.3^5.3) andwas inversely related to age (up to 54 years).Suicide risk increased fur...

the doctor-patient interaction (dpi) plays an important role in the way patients view physicians. thus, response to the question of ''who is a great physician?'' is related to dpi experiences of patients. the aim of this qualitative study was to explore patients' views regarding this subject. based on critical ethnography in one educational hospital in shiraz, iran, the study was performed base...

Hypertrophic obstructive cardiomyopathy (HOCM) describes a pathologic state in which the subaortic region of interventricular septum undergoes significant hypertrophy and fibrosis, resulting septal bowing into left ventricle. The reduced ventricular chamber size altered cardiac function impair diastolic filling, stroke volume, output. This case report evaluates tissue 36-year-old, formalin-emba...

introduction: sleep disorder caused by adenotonsillar hypertrophy has been implicated as a cause of primary and secondary nocturnal enuresis in children.  this study was conducted to investigate the effect of adenotonsillectomy on enuresis in children with adenotonsillar hypertrophy.  materials and methods: this prospective cohort study was conducted in hamadan city in western iran, from april ...

Planar polarity development in the Drosophila wing is under the control of the frizzled (fz) pathway. Recent work has established that the planar polarity (PP) proteins become localized to either the distal, proximal, or both sides of wing cells. Fz and Dsh distal accumulation is thought to locally activate the cytoskeleton to form a hair . Planar polarity effector (PPE) genes such as inturned ...

Case Presentation: A 38-year-old man with hypertrophic cardiomyopathy (HCM) was referred for management of intermittent palpitations and exertional dyspnea with routine activities despite escalated β-blocker therapy. His initial examination was notable for a regular pulse at 72 bpm and harsh systolic murmur that increased with the Valsalva maneuver. A 12-lead electrocardiography revealed sinus ...