The energy demand of cardiomyocytes changes continuously in response to variations cardiac workload. Cardiac excitation-contraction coupling is fueled primarily by adenosine triphosphate (ATP) production oxidative phosphorylation mitochondria. rate mitochondrial metabolism matched the ATP consumption cytosol parallel activation calcium (Ca 2+ ) and diphosphate (ADP). During workload transitions...

Background: Anti-tachycardia pacing (ATP) is a fast and safe method for terminating ventricular tachycardia (VT). Implantable cardioverter defibrillator (ICD) shocks are unpleasant, stressful experiences that have been associated with higher mortality rates than ATP. Determining the factors enhancing efficacy of ATP therapies can minimize appropriate ICD shocks. Objectives: In this study, we in...

A biosensor was developed for directly detecting human immunoglobulin G (IgG) and adenosine triphosphate (ATP) based on stable reproducible gold nanoparticles/polystyrene-b-poly(2-vinylpyridine) (AuNP/PS-b-P2VP) nanocomposites. The substrates were functionalized with carboxylic acid groups the covalent binding of anti-IgG anti-ATP detection IgG ATP (1 to 150 ?g/mL). SEM images nanocomposite sho...

Abstract Nanoscale zero-valent iron (nZVI) and sulfides have been confirmed to be effective in arsenic sequestration from aqueous solution. In this study, attapulgite supported sulfide-modified nanoscale (S-nZVI@ATP) are synthesized realize the superposition effect of enhanced sequestration. The results indicated that nZVI clusters were well disaggregated BET specific surface area increased 19....

Abstract Background In this paper, a simple, enzyme-free, label-free fluorescence, high sensitivity logic gate hairpin aptasensor was developed for adenosine triphosphate (ATP) detection based on graphene oxide (GO) and PicoGreen dye. Methods Using single-strand deoxyribonucleic acid (DNA) as input signal fluorescence output signal, if DNA (DNA-L), (DNA-S), ATP were present at the same time, on...

Type 1 ryanodine receptor (RyR1) releases Ca2+ ions from the sarcoplasmic reticulum of skeletal muscle to initiate contraction. Multiple endogenous and exogenous effectors activate RyR1. Cryo-electron microscopy has identified binding sites three co-activators Ca2+, ATP caffeine, however, mechanism co-regulation synergy between these activators remains be determined. Here, we tested hypothesis ...

El objetivo fue evaluar el efecto del rendimiento de cuatro variedades jamaica sembradas en dos densidades siembra: 8 265 (2) y 13 889 (1) plantas ha-1, condiciones trópico seco Michoacán. diseño experimental bloques completos al azar con arreglo factorial 2 x 4, siembra (factor a) b), nueve repeticiones por tratamiento. Se registraron las variables altura planta (ATP), diámetro tallo basal (DT...

mitochondrial generate cellular energy in the form of atp (adenosine triphosphate) by the process of oxidative phosphorylation (oxphos). most cells contain hundreds of mitochondrial.