esophageal cancer (ec) is the eighth most common cancer and sixth most frequent cause of cancer mortality worldwide. esophageal squamous cell carcinoma (escc) is the most common type of ec. escc develops by progression from premalignant lesions, which are called esophageal squamous dysplasia (esd). prevention is the most effective strategy for controlling this disease. generally, two methods ma...

LEEP conization has become the treatment of choice in patients presenting with high grade intraepithelial lesions (HSILs), especially in cases with negative surgical margins. However, surveillance after such treatment is necessary due to the potential for recurrence. To evaluate the recurrent rate in patients with negative surgical margins after HSIL treatment with LEEP, the medical records of ...

Cutaneous squamous cell carcinoma is a malignant tumour of the keratinising cells epidermis or its appendages. It constitutes 20% skin malignancy. UV radiation exposure most common cause cancer with sun exposed face and upper trunk being site for occurrence. Long term to chemical carcinogen, burn scar, chronic ulcer among other risk factors. Skin biopsy mainstay diagnosis in suspected lesion SC...

Background: The most frequently mutated tumor suppressor gene found in human cancer is p53. In a normal situation, p53 is activated upon the induction of DNA damage to either arrest the cell cycle or to induce apoptosis. However, when mutated, p53 is no longer able to properly accomplish these functions. The aim of this study was to investigate the expression of p53 gene in cases of skin cancer...

Penile cancer is an uncommon primary genitourinary malignancy, the vast majority representing superficial squamous cell carcinomas. However, less common skin cancers, secondary malignancies, mesenchymal neoplasms, and hematopoietic tumors do affect the penis. Medical history, atypical presentation, and deep epicenter of a penile mass may raise question of a nonepithelial neoplasm. We describe a...

the association of squamous cell carcinoma of the larynx with thyroid papillary carcinoma is an unusual finding. from 2004 to 2011, approximately 250 patients underwent laryngectomies due to squamous cell carcinoma of the larynx at the otolaryngology department of khalili hospital, affiliated with shiraz university of medical sciences, shiraz, iran. in three patients, synchronous occurrence of ...

Address correspondence to Steven I. Hajdu, M.D., 1759 Drumcliff Court, Westlake Village, CA 91361, USA; tel 805-496-0691; fax 805-496-0620 Condylomas (condylomata acuminata) and genital warts (verrucous papillomas) have been recognized as human diseases since ancient times [1]. The first microscopic illustration of the squamous cells of a verrucous lesion was published in 1845 [2]. In 1941, an ...